343322-79-2Relevant articles and documents
N-carbamoylated urethane for treating a neuroinflammatory disease
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Paragraph 0123, (2018/02/28)
There is provided a composition for treating a neuroinflammatory disease comprising a N-carbamoylated urethane compound which has an effect of inhibiting the activity of microglia or astrocytes and the production of nitric oxide (NO) and TNF-α, and suppre
Phenotypic screening to identify small-molecule enhancers for glucose uptake: Target identification and rational optimization of their efficacy
Koh, Minseob,Park, Jongmin,Koo, Ja Young,Lim, Donghyun,Cha, Mi Young,Jo, Ala,Choi, Jang Hyun,Park, Seung Bum
supporting information, p. 5102 - 5106 (2014/05/20)
Small-molecule glucose uptake enhancers targeted to myotubes and adipocytes were developed through a phenotypic screening linked with target identification and rational optimization. The target protein of glucose-uptake enhancers was identified as a nucle
PHENOXYACETIC ACID DERIVATIVES AND DRUGS USING THE SAME
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Page/Page column 26, (2010/11/26)
It is intended to provide a novel compound having an excellent agonism to PPARs α/γ and desirable properties as a drug. An agonist to peroxisome proliferator-activated receptors α/γ which is represented by the general formula (I) (wherein Q represents an optionally substituted benzene ring or pyridine ring; R1 and R2 represent each an optionally substituted phenyl group or a 5- to 6-membered aromatic heterocycle group; X, Y and Z independently represent each C, O, S or N; R3 to R9 represent each a hydrogen atom, a lower alkyl group, etc.; and n is an integer of from 0 to 3.