34598-33-9

Basic information

• Product Name: 2-AMINOTOLUENE-5-SULFONIC ACID
• Synonyms: 4-AMINO-M-TOLUENESULFONIC ACID;4-AMINO-3-METHYLBENZENESULFONIC ACID;4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-HEPTADECAFLUOROUNDECANOIC ACID;2-TOLUIDINE-5-SULFONIC ACID;2H,2H,3H,3H-PERFLUOROUNDECANOIC ACID;OTS;2H,2H,3H,3H-PERFLUOROUNDECANOIC ACID, 97% MIN.;3-(Heptadecafluorooctyl)propionic acid
• CAS NO: 34598-33-9
• Molecular Formula: C₁₁H₅F₁₇O₂
• Molecular Weight: 492.13
• EINECS: 252-108-4
• Mol File: 34598-33-9.mol
• Article Data: 13

Chemical Properties

• Melting Point: 93-97 °C
• Boiling Point: 244.9 °C at 760 mmHg
• Flash Point: 101.9 °C
• Appearance: /
• Density: 1.652 g/cm³
• Vapor Pressure: 0.00966mmHg at 25°C
• Refractive Index: 1.308
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly, Heated), Methanol (Slightly)
• PKA: 4.22±0.10(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: 2-AMINOTOLUENE-5-SULFONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOTOLUENE-5-SULFONIC ACID(34598-33-9)
• EPA Substance Registry System: 2-AMINOTOLUENE-5-SULFONIC ACID(34598-33-9)

Safety Data

• Hazard Codes: Xi,C
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• F: 10-21
• HazardClass: IRRITANT
• Hazardous Substances Data: 34598-33-9(Hazardous Substances Data)

Usage

Description

2-AminoToluene-5-Sulfonic Acid, also known as p-aminobenzenesulfonic acid, is an organic compound with the molecular formula C6H7NO3S. It is a white crystalline solid that is soluble in water and has a role as a reagent in various chemical and pharmaceutical applications.

Uses

Used in Chemical Synthesis:
2-AminoToluene-5-Sulfonic Acid is used as a reagent for the synthesis of various organic compounds, particularly in the pharmaceutical industry. It serves as a building block for the production of various drugs and intermediates due to its versatile chemical structure.
Used in Analytical Chemistry:
In analytical chemistry, 2-AminoToluene-5-Sulfonic Acid is used as a buffer component to maintain a stable pH environment during chemical reactions and analyses. Its buffering capacity makes it suitable for various laboratory applications.
Used in Pharmaceutical Industry:
2-AminoToluene-5-Sulfonic Acid is used as an intermediate in the synthesis of pharmaceutical compounds, contributing to the development of new drugs and therapies.
Used in Research and Development:
In the field of research and development, 2-AminoToluene-5-Sulfonic Acid is employed as a research tool to study the properties and interactions of various chemical and biological systems, aiding in the advancement of scientific knowledge.

InChI:InChI=1/C11H5F17O2/c12-4(13,2-1-3(29)30)5(14,15)6(16,17)7(18,19)8(20,21)9(22,23)10(24,25)11(26,27)28/h1-2H2,(H,29,30)

Upstream product

• 113823-56-6 toluene-4-sulfonic acid 1,1,2,2-tetrahydroperfluorodecyl ester 
• 678-39-7 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol 
• 38550-45-7 3-perfluoro-n-octyl-2-iodo-1-propanol 
• 507-63-1 1-iodoheptadecafluorooctane 
• 2043-53-0 2-(n-perfluorooctyl)ethyl iodide 
• 151-50-8 potassium cyanide 
• 124-38-9 carbon dioxide 
• 21652-57-3 1-bromo-1,1,2,2-tetrahydroperfluorodecane 
• 1651-41-8 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecan-1-ol 
• 86624-67-1 4-nitrophenyl 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoate 
• 201230-82-2 carbon monoxide 

Downstream Products

• 162023-70-3 [(S)-5-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecanoylamino)-5-undecylcarbamoyl-pentyl]-carbamic acid benzyl ester 
• 344580-05-8 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecanoic acid (R)-1-phenyl-ethyl ester 
• 165184-83-8 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-1-phenylundecan-1-one 
• 852527-45-8 2,5-dioxopyrrolidine-1-yl 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecanoate 
• 1271773-81-9 C₂₆H₂₅F₁₇N₂O₉ 
• 142010-50-2 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl isocyanate 
• 145441-35-6 N,N-dimethyl, N-(3-F-octyl propyl)-4-ammoniohexanoate 
• 145441-34-5 N,N-dimethyl, N-(3-F-octyl propyl)-4-ammoniopentanoate 
• 145441-33-4 N,N-dimethyl, N-(3-F-octyl propyl)-4-ammoniobutanoate 
• 30295-52-4 N,N-dimethyl, N-<(3-F-octyl)propyl> amine oxide 
• 144584-05-4 2-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecanoylamino)-benzoic acid 

Relevant articles and documents

A fluorocarbon nucleoamphiphile for the construction of actinide loaded microspheres

The synthesis of a novel fluorocarbon based nucleoamphiphile; 2′,3′-O-di-2H,2H,3H,3H-perfluoro-undecanoyl-uridine-5′ -phosphocholine (DiF17UPC) is described. DiF17UPC self-assembles into lamellar organizations unlike 1,2-distearoyluridinophosphocholine (DSUPC) which forms DNA-like helical fibre under similar conditions. The fluorocarbon chains have a significant impact on the supramolecular assemblies formed by the nucleoamphiphiles. The SEM and TEM images collected clearly indicate the formation of microspheres when DiF17UPC is hydrated in the presence of thorium nitrate at high temperature (T > 90 °C). The DiF17UPC/Th4+ microspheres vary in size from 0.5 to 12 μm.

Fluorous derivatives of (1R,2R)-diaminocyclohexane as chiral ligands for metal-catalyzed asymmetric reactions

Perfluoroalkyl-substituted, enantiopure diamines derived from (1R,2R)-diaminocyclohexane were conveniently prepared from readily available precursors. In situ generated metal complexes of these ligands were tested as chiral catalysts in three standard asymmetric reactions (cyclopropanation of styrene, hydrogen transfer reduction of acetophenone, and allylic alkylation of 1,3-diphenyl-2-propenyl acetate) affording enantioselectivities of up to 47% in the copper-catalyzed cyclopropanation of styrene.

FLUOROUS COMPOUND, METHOD OF PREPARING FLUOROUS TAGGED PROTEIN, AND METHOD OF IMMOBILIZING PROTEIN

A fluorous compound, a method of preparing a fluorous tagged protein, and a method of immobilizing protein are provided. The fluorous compound is represented by Y-L-R, wherein Y is a fluorous group; L is a linker, and the linker includes a bivalent group having a sulfo group, a bivalent group having a carboxyl group, or a bivalent group of hydrophilic amino acid; and R is a functional group capable of bonding to protein.