34604-52-9 Usage
Description
Diethylene Glycol Dimethanesulfonate is an organic compound characterized by its white solid appearance. It is known for its chemical properties, which include the presence of mesyl groups that serve as good leaving groups and can also act as protecting groups for primary alcohols. These mesyl groups can be deprotected in the presence of sodium amalgam. Additionally, the hydrophilic PEG linker enhances the compound's water solubility in aqueous media.
Uses
Used in Pharmaceutical Industry:
Diethylene Glycol Dimethanesulfonate is used as an intermediate in the production of alkylating agents for the pharmaceutical industry. Its unique chemical properties make it a valuable component in the synthesis of various drugs, particularly those with alkylating functionalities.
Used in Chemical Synthesis:
In the field of chemical synthesis, Diethylene Glycol Dimethanesulfonate is utilized as a versatile building block for creating a wide range of compounds. Its mesyl groups and PEG linker contribute to its compatibility with various reaction conditions and its ability to form diverse molecular structures.
Used in Research and Development:
Diethylene Glycol Dimethanesulfonate is also employed in research and development settings, where its unique properties can be explored for potential applications in new drug discovery, material science, and other advanced fields. Its reactivity and solubility make it an attractive candidate for further investigation and innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 34604-52-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,6,0 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 34604-52:
(7*3)+(6*4)+(5*6)+(4*0)+(3*4)+(2*5)+(1*2)=99
99 % 10 = 9
So 34604-52-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H14O7S2/c1-14(7,8)12-5-3-11-4-6-13-15(2,9)10/h3-6H2,1-2H3
34604-52-9Relevant articles and documents
MODIFIED CROWN ETHER CATALYSTS. 4. CLEAVAGE OF MACROCYCLIC ETHERS BY EATON'S REAGENT (METHANESULFONIC ACID/PHOSPHORUS PENTOXIDE
Stott, Paul E.,Bradshaw, Jerald S.
, p. 179 - 182 (2007/10/02)
Eaton's reagent (methanesulfonic acid/phosphorous pentoxide) is a superior media for the acylation of benzo crown ether compounds.Benzo-15-crown-5 was cleaved in Eaton's reagent to form methanesulfonate esters of the glycol cleavage products.A comparison of the NMR spectrum of the cleavage products with those of some of the possible products showed that the aliphatic glycols formed the major portion of the cleavage products.