95694-54-5

Basic information

• Product Name: Morpholine, 4-(2-chlorophenyl)-
• CAS NO: 95694-54-5
• Molecular Formula: C10H12ClNO
• Molecular Weight: 197.664
• Mol File: 95694-54-5.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-(2-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-(2-chlorophenyl)-(95694-54-5)
• EPA Substance Registry System: Morpholine, 4-(2-chlorophenyl)-(95694-54-5)

Safety Data

• Hazardous Substances Data: 95694-54-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 147641-13-2 2-chlorophenyl nonaflate 
• 95-57-8 2-monochlorophenol 
• 85070-48-0 2-fluoro-3-chlorobenzaldehyde 
• 1446818-89-8 3-chloro-2-(morpholin-4-yl)benzaldehyde 
• 95-50-1 1,2-dichloro-benzene 
• 34604-52-9 diethylene glycol dimesylate 
• 95-51-2 o-chloroaniline 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 23328-69-0 4-chloromorpholine 
• 348-51-6 1-chloro-2-fluorobenzene 
• 694-80-4 2-bromo-1-chlorobenzene 
• 111-46-6 diethylene glycol 

Downstream Products

• 1444746-09-1 4-(4'-methoxy-[1,1'-biphenyl]-2-yl)morpholine 
• 1152887-64-3 N-benzyl-2-morpholinoaniline 
• 28276-88-2 2-(N-(2-chlorophenyl)formamido)ethyl formate 

Relevant articles and documents

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N-heterocyclic carbene-Pd(II)-2-methyl-4,5-dihydrooxazole complex-catalyzed highly chemoselective mono-amination of dichlorobenzenes

The palladium-catalyzed chemoselective mono-amination of dichlorobenzenes was reported in this paper. Under the suitable conditions, all reactions involving the three isomers of dichlorobenzenes with various secondary and primary amines in the presence of

Transition-Metal-Catalyzed Amination of Aryl Fluorides

Arene activation via transition-metal (TM) η 6-coordination has merged as a powerful method to diversify the aromatic C-F bond, which is relatively less reactive due to its high bond energy. However, this strategy in general requires to use largely excess arenes or TM η 6-complexes as the substrates. Herein, we highlight our recent work on the catalytic S NAr amination of electron-rich and electron-neutral aryl fluorides that are inert in classical S NAr reactions. This protocol enabled by a Ru/hemilabile ligand catalyst covers a broad scope of substrates without wasting arenes. Mechanistic studies revealed that the nucleo?-philic substitution proceeded on a Ru η 6-arene complex, and the hemilabile ligand significant promoted the arene dissociation.