347190-80-1

Basic information

• Product Name: 2,5-bis(4-nitro-2-trifluorophenyl)furan
• Synonyms: 2,5-bis(4-nitro-2-trifluorophenyl)furan
• CAS NO: 347190-80-1
• Molecular Weight: 446.262
• Mol File: 347190-80-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,5-bis(4-nitro-2-trifluorophenyl)furan(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-bis(4-nitro-2-trifluorophenyl)furan(347190-80-1)
• EPA Substance Registry System: 2,5-bis(4-nitro-2-trifluorophenyl)furan(347190-80-1)

Safety Data

• Hazardous Substances Data: 347190-80-1(Hazardous Substances Data)

Upstream product

• 367-67-9 2-bromo-5-nitro-benzotrifluoride 
• 193361-76-1 2,5-bis(tri-n-butylstannyl)furan 

Downstream Products

• 347190-91-4 2,5-bis(2-trifluoromethyl-4-N,N'-di-BOCguanidinophenyl)furan 

Relevant articles and documents

The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani

The in vitro activity of 20 dicationic molecules containing either diguanidino or reversed amidine cationic groups were evaluated versus Trypanosoma cruzi and Leishmania donovani. The most active compounds were in the reversed amidine series and six exhibited IC50 values of less than 1 μmol versus T. cruzi and five gave similar values versus L. donovani.

Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents

Dicationic 2,5-bis(4-guanidinophenyl)furans 5a-5f, 2,5-bis[4- (arylimino)aminophenyl]furans 6a-6b and 6e-6k, and 2,5-bis[4-(alkylimino)aminophenyl]furans 6c-6d have been synthesized starting from 2,5-bis[tri-n-butylstannyl]furan. Thermal melting studies w