3492-66-8

Basic information

• Product Name: benzyl hydrodisulfide
• Synonyms: benzyl hydrodisulfide
• CAS NO: 3492-66-8
• Molecular Formula: C₇H₈S₂
• Molecular Weight: 156.27
• Mol File: 3492-66-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 237°Cat760mmHg
• Flash Point: 97.1°C
• Appearance: /
• Density: 1.168g/cm³
• Vapor Pressure: 0.0706mmHg at 25°C
• Refractive Index: 1.621
• PKA: 8.37±0.10(Predicted)
• CAS DataBase Reference: benzyl hydrodisulfide(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl hydrodisulfide(3492-66-8)
• EPA Substance Registry System: benzyl hydrodisulfide(3492-66-8)

Safety Data

• Hazardous Substances Data: 3492-66-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H8S2/c8-9-6-7-4-2-1-3-5-7/h1-5,8H,6H2

Upstream product

• 5797-02-4 acetyl benzyl disulfide 
• 56-23-5 tetrachloromethane 
• 56554-80-4 1-chloro-heptadec-8-ene 

Downstream Products

• 40096-00-2 benzyl 2-hydroxyethyl trisulfide 
• 347146-27-4 2-Benzylthio-4-carboxamidepyridine 
• 6493-73-8 dibenzyltrisulfide 
• 94785-40-7 methyl 2-(benzyldisulfanyl)acetate 
• 97195-86-3 dibenzyl hexasulfide 
• 17246-63-8 dibenzyl pentasulfide 
• 4816-54-0 dibenzyl tetrasulfide 

Relevant articles and documents

An Esterase-Sensitive Prodrug Approach for Controllable Delivery of Persulfide Species

A strategy to deliver a well-defined persulfide species in a biological medium is described. Under near physiological conditions, the persulfide prodrug can be activated by an esterase to generate a “hydroxymethyl persulfide” intermediate, which rapidly collapses to form a defined persulfide. Such persulfide prodrugs can be used either as chemical tools to study persulfide chemistry and biology or for future development as H2S-based therapeutic reagents. Using the persulfide prodrugs developed in this study, the reactivity between S-methyl methanethiosulfonate (MMTS) with persulfide was unambiguously demonstrated. Furthermore, a representative prodrug exhibited potent cardioprotective effects in a murine model of myocardial ischemia-reperfusion (MI/R) injury with a bell shape therapeutic profile.