34966-49-9

Basic information

• Product Name: Methyl 2-(2-chlorophenyl)-2-oxoacetate
• Synonyms: Methyl 2-(2-chlorophenyl)-2-oxoacetate;Ethyl 2-(2-chlorophenyl)-2-oxoacetate;2-Chloro-alpha-oxobenzeneacetic acid methyl ester;Methyl (2-chlorophenyl)oxoacetate;Benzeneacetic acid, 2-chloro-α-oxo-, methyl ester
• CAS NO: 34966-49-9
• Molecular Formula: C₉H₇ClO₃
• Molecular Weight: 212.62966
• Mol File: 34966-49-9.mol
• Article Data: 31

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 2-(2-chlorophenyl)-2-oxoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(2-chlorophenyl)-2-oxoacetate(34966-49-9)
• EPA Substance Registry System: Methyl 2-(2-chlorophenyl)-2-oxoacetate(34966-49-9)

Safety Data

• Hazardous Substances Data: 34966-49-9(Hazardous Substances Data)

Usage

General Description

Methyl 2-(2-chlorophenyl)-2-oxoacetate is a chemical compound with the molecular formula C9H7ClO3. It is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and organic compounds. Methyl 2-(2-chlorophenyl)-2-oxoacetate is a white to off-white solid with a melting point of around 105-107°C. Methyl 2-(2-chlorophenyl)-2-oxoacetate is known to be a mild irritant to skin, eyes, and respiratory system, and must be handled with care to prevent any adverse health effects. It is important to use proper protective equipment and follow all safety protocols when working with this chemical.

Upstream product

• 57486-68-7 methyl (2-chlorophenyl)acetate 
• 156276-21-0 rac-methyl 2-chloromandelate 
• 67-56-1 methanol 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 10421-85-9 2-chloromandelic acid 
• 2444-36-2 2'-chloro-benzeneacetic acid 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 2856-63-5 2-Chlorophenylacetonitrile 
• 35022-42-5 2-chlorobenzoyl cyanide 
• 74-88-4 methyl iodide 
• 85259-19-4 methyl 2-bromo-2-(2-chlorophenyl)acetate 
• 873-31-4 2-chlorophenylacetylene 
• 26118-14-9 o-chlorobenzoylformic acid 
• 553-90-2 Dimethyl oxalate 

Downstream Products

• 32345-60-1 methyl (S)-2-hydroxy-2-(2-chlorophenyl)acetate 
• 32345-59-8 methyl (R)-2-chloromandelate 
• 1268358-78-6 1-(2-chlorophenyl)-2-methoxy-2-oxoethyl thiophene-2-carboxylate 
• 1268358-85-5 1-(2-chlorophenyl)-2-methoxy-2-oxoethyl 5-chlorothiophene-2-carboxylate 
• 156276-21-0 rac-methyl 2-chloromandelate 
• 1268358-82-2 1-(2-chlorophenyl)-2-methoxy-2-oxoethyl 3,5-dinitrobenzoate 
• 1268358-80-0 1-(2-chlorophenyl)-2-methoxy-2-oxoethyl 4-fluorobenzoate 
• 1268358-84-4 1-(2-chlorophenyl)-2-methoxy-2-oxoethyl 3-nitrobenzoate 
• 1268358-79-7 1-(2-chlorophenyl)-2-methoxy-2-oxoethyl benzoate 
• 1268358-81-1 1-(2-chlorophenyl)-2-methoxy-2-oxoethyl 4-cyanobenzoate 
• 1268358-83-3 1-(2-chlorophenyl)-2-methoxy-2-oxoethyl 3,4-dichlorobenzoate 
• 32345-65-6 (DL)-o-chlorophenyl-1,2-ethanediol 
• 1403825-55-7 methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate 
• 252025-50-6 methyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate 

Relevant articles and documents

Tandem Photoredox-Chiral Phosphoric Acid Catalyzed Radical-Radical Cross-Coupling for Enantioselective Synthesis of 3-Hydroxyoxindoles

A photochemical protocol that couples diarylamines and α-ketoesters to afford the chiral 3-hydroxyoxindoles through tandem photoredox and chiral phosphoric acid catalysis is developed. The reaction involves an enantioselective photochemical radical-radical cross-coupling process. The chiral phosphoric acid is discovered to play crucial roles by decreasing the reductive potentials of α-ketoesters and stereocontrolling the downstream asymmetric radical-radical cross-coupling via the formation of pentacoordinate complex.

Synthetic method of racemic clopidogrel

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Carbene-Catalyzed Enantioselective Aromatic N-Nucleophilic Addition of Heteroarenes to Ketones

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