35094-46-3

Basic information

• Product Name: ADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER SODIUM SALT
• Synonyms: SP-ATP-ALPHA-S SODIUM SALT;ADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER SODIUM SALT;ADENOSINE 5''-(GAMMA-THIO)TRIPHOSPHATE;Adenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution
• CAS NO: 35094-46-3
• Molecular Formula: C₁₀H₁₆N₅O₁₂P₃S
• Molecular Weight: 523.25
• Mol File: 35094-46-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 901.8±75.0 °C(Predicted)
• Appearance: /
• Density: 2.56±0.1 g/cm3(Predicted)
• PKA: 0.67±0.50(Predicted)
• CAS DataBase Reference: ADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: ADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER SODIUM SALT(35094-46-3)
• EPA Substance Registry System: ADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER SODIUM SALT(35094-46-3)

Safety Data

• Hazardous Substances Data: 35094-46-3(Hazardous Substances Data)

Usage

Definition

ChEBI: A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.

Upstream product

• 58-64-0 adenosine 5'-diphosphate 

Downstream Products

• 58-64-0 adenosine 5'-diphosphate 
• 79049-97-1 uridine-5'-O-(3-thiotriphosphate) 

Relevant articles and documents

Practical Enzymatic Synthesis of Adenosine 5'-O-(3-Thiotriphosphate) (ATP-γ-S)

An enzymatic procedure for the synthesis of adenosine 5'-O-(3-thiotriphosphate) (ATP-γ-S) on a 50-mmol scale from dihydroxyacetone, sodium thiophosphate, ADP, and phosphoenol pyruvate is described.The synthesis uses polyacrylamide gel immobilized glycerokinase coupled to a pyruvate kinase catalyzed ATP cofactor regeneration system, and polyacrylamide gel immobilized triosephosphate isomerase, glyceraldehyde 3-phosphate dehydrogenase, and phosphoglycerate kinase coupled to a lactate dehydrogenase catalyzed NAD cofactor regeneration system.The ATP-γ-S is purified by adsorption on Dowex 1 and isolated as the sodium or barium salts in ca. 90 percent purity.