35166-37-1

Basic information

• Product Name: 3-(Chloromethyl)-5-methylisoxazole
• Synonyms: 3-CHLOROMETHYL-5-METHYLISOXAZOLE;BUTTPARK 27\08-50;3-(Chloromethyl)-5-methylisoxazole, 95+%;3-(chloroMethyl)-5-Methyl-1,2-oxazole
• CAS NO: 35166-37-1
• Molecular Formula: C₅H₆ClNO
• Molecular Weight: 131.56
• Product Categories: Oxazole&Isoxazole;Heterocycle
• Mol File: 35166-37-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 93 °C
• Flash Point: 83.9ºC
• Appearance: /
• Density: 1.202 g/cm³
• Vapor Pressure: 0.22mmHg at 25°C
• Refractive Index: 1.482
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -3.39±0.12(Predicted)
• CAS DataBase Reference: 3-(Chloromethyl)-5-methylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Chloromethyl)-5-methylisoxazole(35166-37-1)
• EPA Substance Registry System: 3-(Chloromethyl)-5-methylisoxazole(35166-37-1)

Safety Data

• Hazard Codes: Xi,C
• Statements: 34-41
• Safety Statements: 26-36/37/39-45-39
• RIDADR: 3265
• Hazardous Substances Data: 35166-37-1(Hazardous Substances Data)

Usage

General Description

3-(Chloromethyl)-5-methylisoxazole is a chemical compound that belongs to the broader group of isoxazoles, which are organic compounds containing an isoxazole ring. The specific structure of this compound includes an isoxazole ring connected to a chloromethyl group at the third position and a methyl group at the fifth position. 3-(Chloromethyl)-5-methylisoxazole is primarily used in scientific research and for the synthesis of other complex compounds. It may pose some risks due to its chemical reactivity, so appropriate safety precautions should be undertaken while handling this compound. Currently, there is no specific information available about its potential for toxicity or environmental impact.

InChI:InChI=1/C5H6ClNO/c1-4-2-5(3-6)7-8-4/h2H,3H2,1H3

Upstream product

• 3209-72-1 ethyl 5-methylisoxazole-3-carboxylate 
• 35166-33-7 (5-methyl-isoxazol-3-yl)-methanol 

Downstream Products

• 100960-41-6 2-amino-3-(5-methyl-isoxazol-3-yl)-propionic acid 
• 172475-36-4 1-<(5-Methylisoxazol-3-yl)methyl>pyrazole 
• 74704-94-2 N-(5-methyl-3-isoxazolylmethyl)-2,6-dimethylaniline 
• 344886-74-4 2-(5-Methyl-isoxazol-3-ylmethoxy)-phenol 
• 57612-87-0 (5-methyl-1,2-oxazol-3-yl)acetic acid 
• 145441-07-2 3-(2,6-dimethylphenoxymethyl)-5-methyl-3-isoxazole 

Relevant articles and documents

SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.

Substituted enaminones, their derivatives and uses thereof

The present invention is related substituted enaminones represented by a compound of Formula I that are novel allosteric modulators of α7 nAChRs. The invention also discloses the treatment of disorders that are responsive to enhancement of acetylcholine a

Di-heterocyclic compounds and their use as antiviral agents

Compounds of the formulas: STR1 wherein Het is an oxazole or oxazine moiety; X is O, S or SO, n is an integer from 3 to 9, Y is an aliphatic bridge; and the various R groups represent hydrogen or various substituents as described herein, are useful as antiviral agents, especially against picornaviruses. N-(Chloroalkyl)amide intermediates for the compounds of Formula I are also active as antiviral agents. Related compounds outside the scope of the above formulas are also disclosed.