35193-97-6

Basic information

• Product Name: 8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>octan-3-one
• Synonyms: 8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>octan-3-one
• CAS NO: 35193-97-6
• Molecular Weight: 261.321
• Mol File: 35193-97-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>octan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>octan-3-one(35193-97-6)
• EPA Substance Registry System: 8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>octan-3-one(35193-97-6)

Safety Data

• Hazardous Substances Data: 35193-97-6(Hazardous Substances Data)

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 542-05-2 acetonedicarboxylic acid 
• 10272-07-8 3.5-dimethoxyaniline 

Downstream Products

• 94635-18-4 2,4-diamino-6-chloro-5-<8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>oct-3-exo-yl>pyrimidine 
• 94635-21-9 2,6-diamino-5-<8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>oct-3-exo-yl>pyrimidin-4(3H)-one 
• 94635-19-5 ethyl cyano<8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>oct-3-ylidene>acetate 

Relevant articles and documents

5-(N-Arylnortropan-3-yl)- and 5-(N-Arylpiperidin-4-yl)-2,4-diaminopyrimidines. Novel Inhibitors of Dihydrofolate Reductase

Based on a computer-assisted analysis of the three-dimensional structure of the binary complex of E.coli dihydrofolate reductase (DHFR) with methotrexate, 5-(N-arylnortropan-3-yl)- and 5-(N-arylpiperidin-4-yl)-2,4-diaminopyrimidines 2 and 4 were designed