94635-19-5

Basic information

• Product Name: Acetic acid, cyano[8-(3,5-dimethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ylidene]-, ethyl ester
• CAS NO: 94635-19-5
• Molecular Formula: C20H24N2O4
• Molecular Weight: 356.422
• Mol File: 94635-19-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid, cyano[8-(3,5-dimethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ylidene]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, cyano[8-(3,5-dimethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ylidene]-, ethyl ester(94635-19-5)
• EPA Substance Registry System: Acetic acid, cyano[8-(3,5-dimethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ylidene]-, ethyl ester(94635-19-5)

Safety Data

• Hazardous Substances Data: 94635-19-5(Hazardous Substances Data)

Upstream product

• 10272-07-8 3.5-dimethoxyaniline 
• 542-05-2 acetonedicarboxylic acid 
• 35193-97-6 8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>octan-3-one 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 94635-18-4 2,4-diamino-6-chloro-5-<8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>oct-3-exo-yl>pyrimidine 
• 104404-90-2 2,4-diamino-6-chloro-5-<8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>oct-3-endo-yl>pyrimidine 
• 94635-21-9 2,6-diamino-5-<8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>oct-3-exo-yl>pyrimidin-4(3H)-one 
• 104404-88-8 2,6-diamino-5-<8-(3,5-dimethoxyphenyl)-8-azabicyclo<3.2.1>oct-3-endo-yl>pyrimidin-4(3H)-one 

Relevant articles and documents

5-(N-Arylnortropan-3-yl)- and 5-(N-Arylpiperidin-4-yl)-2,4-diaminopyrimidines. Novel Inhibitors of Dihydrofolate Reductase

Based on a computer-assisted analysis of the three-dimensional structure of the binary complex of E.coli dihydrofolate reductase (DHFR) with methotrexate, 5-(N-arylnortropan-3-yl)- and 5-(N-arylpiperidin-4-yl)-2,4-diaminopyrimidines 2 and 4 were designed