35194-36-6

Basic information

• Product Name: 4-HEXENOIC ACID
• Synonyms: 4-HEXENOIC ACID;hex-4-enoic acid;4-Hexenoicacid,cis+trans,98%;4-hexenoic acid, cis + trans;Hex-4-enoic acid, mixture of cis/trans isomers 98%;Hex-4-enoic acid 98%
• CAS NO: 35194-36-6
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.14
• EINECS: 252-427-9
• Mol File: 35194-36-6.mol
• Article Data: 14

Chemical Properties

• Melting Point: 17.3°C (estimate)
• Boiling Point: 100°C 10mm
• Flash Point: 100°C/10mm
• Appearance: /
• Density: 0.958
• Vapor Pressure: 0.111mmHg at 25°C
• Refractive Index: 1.4390
• BRN: 1720995
• CAS DataBase Reference: 4-HEXENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HEXENOIC ACID(35194-36-6)
• EPA Substance Registry System: 4-HEXENOIC ACID(35194-36-6)

Safety Data

• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 35194-36-6(Hazardous Substances Data)

Usage

General Description

4-Hexenoic acid, also known as sorbic acid, is a naturally occurring organic compound with the chemical formula C6H10O2. It is a colorless liquid with a strong, pungent odor and is found in a variety of natural sources, including certain fruits and berries. It is commonly used as a food preservative due to its antimicrobial properties, inhibiting the growth of mold and fungi. It is also used in cosmetics and personal care products as a fragrance additive, and in the pharmaceutical industry as a precursor for the synthesis of other compounds. Additionally, 4-Hexenoic acid has potential applications in the production of biodegradable polymers and as a precursor for the synthesis of various organic compounds.

InChI:InChI=1/C6H10O2/c1-2-3-4-5-6(7)8/h2-3H,4-5H2,1H3,(H,7,8)/b3-2-

Upstream product

• 22768-09-8 (E)-Hex-4-enoic acid cyano-dimethyl-methyl ester 
• 110-44-1 sorbic Acid 
• 2396-79-4 E,Z-4-hexenecarboxylic acid methyl ester 
• 821-41-0 5-Hexen-1-ol 
• 598-32-3 2-hydroxy-3-butene 
• 802294-64-0 propionic acid 
• 78-39-7 Triethyl orthoacetate 
• 6126-50-7 hex-4-en-1-ol 
• 1577-22-6 5-hexenoic acid 
• 80466-34-8 2,4-hexadienal 
• 3128-06-1 5-ketohexanoic acid 
• 7782-77-6 cis-nitrous acid 
• 60-32-2 6-aminohexanoic acid 
• 1089919-71-0 2-methyl-6-oxo-tetrahydro-pyran-3-carboxylic acid 

Downstream Products

• 142-62-1 hexanoic acid 
• 695-06-7 hexan-4-olide 
• 504-60-9 penta-1,3-diene 
• 29518-82-9 2,8-decadiyne 
• 2396-79-4 E,Z-4-hexenecarboxylic acid methyl ester 
• 108752-32-5 N-phenylhex-4-enamide 
• 6126-50-7 hex-4-en-1-ol 
• 14017-81-3 methyl (E)-hex-4-enoate 
• 13894-60-5 methyl (Z)-hex-4-enoate 
• 110-15-6 succinic acid 

Relevant articles and documents

Catalytic hydrogenation of sorbic acid using pyrazolyl palladium(II) and nickel(II) complexes as precatalysts

We have prepared several pyrazolyl palladium and nickel complexes ([(L1)PdCl2] (1), [(L2) PdCl2] (2), [(L3) PdCl2] (3), [(L1) NiBr2] (4), [(L2) NiBr2] (5) and [(L3) NiBr2] (6)) by reacting 3,5-dimethyl-1H-pyrazole (L1), 3,5-di-tert-butyl-1H-pyrazole (L2) and 5-ferrocenyl-1H-pyrazole(L3) with [PdCl2(NCMe)2] or [NiBr2(DME)] to afford mononuclear palladium and nickel complexes, respectively. These complexes were then investigated as pre-catalysts in the hydrogenation of 2,4-hexadienoic acid (sorbic acid). The active catalysts from these complexes demonstrate significant activities under mild experimental conditions. Additionally, the active catalysts show that the hydrogenation of sorbic acid proceeds in a sequential manner, where the less hindered C=C bond (4-hexenoic acid) is preferentially reduced over the more hindered C=C bond (2-hexenoic acid).

Iridium-Catalyzed γ-Selective Hydroboration of γ-Substituted Allylic Amides

Reported here for the first time is the Ir-catalyzed γ-selective hydroboration of γ-substituted allylic amides under mild reaction conditions. A variety of functional groups could be compatible with reaction conditions, affording γ-branched amides in good yields with ≤97% γ-selectivity. We have also demonstrated that the obtained borylated products could be used in a series of C-O, C-F, C-Br, and C-C bond-forming reactions.

Highly active bidentate N-heterocyclic carbene/ruthenium complexes performing dehydrogenative coupling of alcohols and hydroxides in open air

Eight bidentate NHC/Ru complexes, namely [Ru]-1-[Ru]-8, were designed and prepared. In particular, [Ru]-2 displayed extraordinary performance even in open air for the dehydrogenative coupling of alcohols and hydroxides. Notably, an unprecedentedly low catalyst loading of 250 ppm and the highest TON of 32 800 and TOF of 3200 until now were obtained.