35212-99-8

Basic information

• Product Name: 5,6-DIMETHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 5,6-DIMETHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER;METHYL 5,6-DIMETHOXY-1-BENZOTHIOPHENE-2-CARBOXYLATE
• CAS NO: 35212-99-8
• Molecular Formula: C₁₂H₁₂O₄S
• Molecular Weight: 252.29
• Mol File: 35212-99-8.mol
• Article Data: 9

Chemical Properties

• Melting Point: 157-158 °C
• Boiling Point: 368°C at 760 mmHg
• Flash Point: 176.4°C
• Appearance: /
• Density: 1.268g/cm³
• Vapor Pressure: 1.31E-05mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: 5,6-DIMETHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-DIMETHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(35212-99-8)
• EPA Substance Registry System: 5,6-DIMETHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(35212-99-8)

Safety Data

• Hazardous Substances Data: 35212-99-8(Hazardous Substances Data)

Usage

General Description

5,6-Dimethoxy-benzo[b]thiophene-2-carboxylic acid methyl ester is a compound with the chemical formula C13H12O4S. It is a methyl ester derivative of benzo[b]thiophene-2-carboxylic acid, a heterocyclic compound with potential pharmaceutical applications. This chemical is a benzothiophene derivative, which belongs to the family of benzene and substituted derivatives. It is primarily used in pharmaceutical research and drug development due to its potential biological activities. The compound is known for its anti-inflammatory and antimicrobial properties, and it is being studied for its potential applications in the treatment of various diseases and disorders.

InChI:InChI=1/C12H12O4S/c1-14-8-4-7-5-11(12(13)16-3)17-10(7)6-9(8)15-2/h4-6H,1-3H3

Upstream product

• 1649501-87-0 methyl (Z)-2-(3,4-dimethoxyphenylthio)-3-(dimethylamino)acrylate 
• 193549-37-0 methyl 2-(3,4-dimethoxyphenylthio)acetate 
• 700-96-9 3,4-dimethoxythiophenol 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 2365-48-2 Methyl thioglycolate 
• 2316-26-9 3,4-dimethoxycinnamic acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 71797-90-5 methyl 3-chloro-5,6-dimethoxybenzo[b]thiophene-2-carboxylate 
• 71924-62-4 2-fluoro-4,5-dimethoxybenzaldehyde 
• 23046-03-9 5,6-dimethoxy-benzo[b]thiophene-2-carboxylic acid 

Downstream Products

• 1295537-10-8 methyl 2-(5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoate 
• 126674-91-7 2-(5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoic acid 
• 1295537-09-5 2-(1,1-dioxo-5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoic acid 
• 23046-03-9 5,6-dimethoxy-benzo[b]thiophene-2-carboxylic acid 
• 91715-47-8 5,6-dimethoxybenzo[b]thiophene 

Relevant articles and documents

BENZOTHIOPHENE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

A compound represented by formula (I) or a pharmaceutically acceptable salt, a stereoisomer, a tautomer, a polymorph, a solvate, an N-oxide, an isotope labeled compound, a metabolite or a prodrug thereof, a pharmaceutical composition and a pill container comprising same, a preparation method therefor, and the use thereof in the preparation of drugs for preventing or treating STING-mediated related diseases.

Amide compound and preparation method and application thereof

The invention relates to an amide compound and a preparation method and application thereof. Specifically, the present invention relates to a compound of formula I or a pharmaceutically acceptable salt, stereoisomer, tautomer, polymorph, solvate, N-oxide, isotope labeled compound, metabolite or prodrug thereof, pharmaceutical compositions and kits comprising the same, processes for their preparation and their use in the preparation of medicaments for the treatment of STING-mediated related diseases.

BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS

Compounds of general formula (Ia), compounds of general formula (Ia′), compounds of general formula (Ib), compounds of general formula (Ib′), compounds of general formula (I), compounds of general formula (I′), and their pharmaceutically acceptable salts,