355-42-0

Basic information

• Product Name: PERFLUOROHEXANE
• Synonyms: Perfluorohexane Mixed isomers;Perfluorohexanes, 98+%;3M FC-72 Fluorinet, PF-5060 3M;PFC-51-14;Perfluoro-compound FC-72(TM);Perfluorohexane ,99%;Perfluoro-compound FC-72§3;Perfluoro-coMpound FC-72100GR
• CAS NO: 355-42-0
• Molecular Formula: C₆F₁₄
• Molecular Weight: 338.04
• EINECS: 206-585-0
• Product Categories: organofluorine compounds;refrigerants
• Mol File: 355-42-0.mol
• Article Data: 28

Chemical Properties

• Melting Point: −4 °C(lit.)
• Boiling Point: 58-60 °C(lit.)
• Flash Point: 56-60°C
• Appearance: Clear colorless/Liquid
• Density: 1.669 g/mL at 25 °C(lit.)
• Vapor Pressure: 228mmHg at 25°C
• Refractive Index: n20/D 1.252(lit.)
• Water Solubility: Immiscible with water.
• Stability: Stable. Incompatible with strong oxidizing agents.
• Merck: 14,7157
• BRN: 1802113
• CAS DataBase Reference: PERFLUOROHEXANE(CAS DataBase Reference)
• NIST Chemistry Reference: PERFLUOROHEXANE(355-42-0)
• EPA Substance Registry System: PERFLUOROHEXANE(355-42-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: 2810
• WGK Germany: 3
• RTECS: MO4310000
• TSCA: T
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 355-42-0(Hazardous Substances Data)

Usage

Description

Perfluorohexane, also known as Tetradecafluorohexane, is a colorless liquid with unique chemical and physical properties. It is biologically inert, chemically stable, and has the ability to dissolve gases, including oxygen, to a higher concentration than ordinary organic solvents. This characteristic is due to the weak intermolecular forces between perfluorohexane molecules, which allows for "space" for gas molecules to partition into the liquid.

Uses

Used in Electronics Industry:
Perfluorohexane is used as a coolant and test bath medium in the electronics industry. Its non-toxic, non-ozone-depleting, and inert reaction medium properties make it suitable for electronic cooling liquids and insulators.
Used in Chemical Reactions:
Perfluorohexane serves as a photosensitizer in fluorous biphasic singlet oxygenation and as an inert reaction medium. It is particularly useful for photooxidation reactions.
Used in Medical Applications:
Due to its ability to dissolve gases, including oxygen, perfluorohexane has been experimentally used in treating burn victims. It can be used to fill the lungs of patients, allowing them to breathe without the complications of pulmonary edema that can occur when the lungs are severely burnt.
Used in Lubricants and Coatings:
Perfluorohexane is used as a dispersant for lubricants, mold release agents, and protective coatings.
Used in Polymerizations and Separation Processes:
It acts as a reaction medium for polymerizations, purification, and separation processes.
Used in Solvent Applications:
Perfluorohexane is used as a solvent for the removal of halogenated lubricants, oils, and greases.
Used in Food Industry:
It serves as a carrier for halogenated material and is used for quick-cooling or freezing foods.
Used in Heat Transfer:
Perfluorohexane is utilized as a heat-transfer fluid.

Purification Methods

Purify the fluorohexane by fractional freezing. The methods described for perfluoroheptane should be applicable here. [Beilstein 1 IV 348.]

InChI:InChI=1/C6F14/c7-1(8,3(11,12)5(15,16)17)2(9,10)4(13,14)6(18,19)20

Upstream product

• 110-54-3 hexane 
• 922-61-2 3-methyl-2-pentene 
• 754-34-7 1,1,1,2,2,3,3-heptafluoro-3-iodo-propane 
• 14352-61-5 methyl cyclohexylacetate 
• 336-59-4 heptafluorobutyric anhydride 
• 375-22-4 heptafluorobutyric Acid 
• 311-89-7 Perfluorotributylamine 
• 123-91-1 1,4-dioxane 
• 423-41-6 perfluoropropanesulfonic acid 
• 626-58-4 4-methylpiperidin 
• 111-49-9 hexamethylene imine 
• 116-15-4 perfluoropropylene 
• 373-80-8 trifluoromethyl sulfur pentafluoride 
• 13709-36-9 xenon difluoride 

Downstream Products

• 75-73-0 carbon tetrafluoride 
• 75-72-9 chlorotrifluoromethane 
• 90499-30-2 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-octadecane 
• 174861-40-6 5-Octyl-2-(4-(1,1-dihydroperfluoro-5-(2-butoxyethoxy) pentoxy)phenyl)pyrimidine 
• 174861-41-7 5-Octyl-2-(4-(1,1-dihydroperfluoro-6-(2-butoxyethoxy) hexyloxy)phenyl)pyrimidine 
• 109574-84-7 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-8-iodotetradecane 

Relevant articles and documents

THE CHEMISTRY OF DIACYL PEROXIDES - VIII. THE REACTIONS BETWEEN POLYFLUORODIACYL PEROXIDES AND 2-NITRO-2-NITROSOPROPANE--GENERATION OF BIS(POLYFLUOROALKYL) NITROXIDES

Thermal decomposition of 2-nitro-2-nitrosopropane (4) in F113 (CCl2F-CClF2) solution involves C-NO bond fission and forms acetone as the major product.In the presence of polyfluorodiacyl peroxide (3), the oxidation of 4 by 3 to 2,2-dinitropropane (5) is the predominant reaction and bis(polyfluoroalkyl) nitroxide (1) is generated as one of the by-products.

A preparation method of the whole fluorine hexanone (by machine translation)

The invention discloses a full-fluorine hexanone preparation method, the method to hexafluoropropylene as raw materials, in alkyl formamine villaumite presence, through oxygen oxidizing part of the hexafluoropropylene generating hexafluoropropene, hexafluoropropylene oxide in the aminopyridine resin solid alkali under the action of the acylation reaction produce the full fluorine propionyl fluoride, then full fluorination coins with unreacted hexafluoropropylene in catalytic condensation under the fluorine ions to prepare the full fluorine hexanone, the above reaction is performed in a reactor are in the pipeline. The technology of the invention low cost, reaction selectivity and high yield, high purity of the product, after treatment is simple, pollution-free, is a green synthesis process. Suited to large-scale production of clean production technology. (by machine translation)

Preparation method for perfluoroalkane

The invention discloses a preparation method for perfluoroalkane. The preparation method comprises the following steps: adding a fluorination reagent into a reaction vessel, stirring the fluorination reagent at room temperature, introducing fluorine-nitrogen gas mixture into the reaction vessel for activation of the fluorination reagent and continuing stirring for half an hour, wherein the concentration of fluorine gas in the fluorine-nitrogen gas mixture is 0.5 to 10%, and the molar weight of the fluorine-nitrogen gas mixture is 1 to 5% of the molar weight of the fluorination reagent; after completion of stirring, relieving residual pressure in the reaction vessel, and adding perfluoroalkyl halide and a solvent into the reaction vessel for a reaction at 150 to 200 DEG C for 5 to 10 h, wherein a mol ratio of perfluoroalkyl halide to the fluorination reagent is (1: 1) to (1: 2), and a mol ratio of perfluoroalkyl halide to the solvent is (1: 5) to (1: 15); and after a reaction product is obtained upon completion of the reaction, cooling the reaction product to room temperature and distilling the reaction product to obtain perfluoroalkane. The method provided by the invention has the advantages of simple equipment, high operation security, etc.