35534-19-1

Basic information

• Product Name: 2-(Methylamino)-1-phenylethanone
• Synonyms: 2-METHYLAMINO-1-PHENYL-ETHANONE HYDROCHLORIDE;2-(Methylamino)-1-phenylethanone;alpha-(Methylamino)acetophenone;Ethanone, 2-(methylamino)-1-phenyl-
• CAS NO: 35534-19-1
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.19
• Mol File: 35534-19-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 245 ºC
• Flash Point: 104 ºC
• Appearance: /
• Density: 1.019
• Vapor Pressure: 0.03mmHg at 25°C
• Refractive Index: 1.521
• CAS DataBase Reference: 2-(Methylamino)-1-phenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methylamino)-1-phenylethanone(35534-19-1)
• EPA Substance Registry System: 2-(Methylamino)-1-phenylethanone(35534-19-1)

Safety Data

• Hazardous Substances Data: 35534-19-1(Hazardous Substances Data)

Usage

General Description

2-(Methylamino)-1-phenylethanone, also known as methamphetamine, is a synthetic stimulant drug that affects the central nervous system. It is a powerful and highly addictive substance, with effects similar to those of amphetamine, including increased energy, alertness, and euphoria. Methamphetamine is commonly used as a recreational drug, but it also has limited medical uses for the treatment of attention deficit hyperactivity disorder (ADHD) and obesity. It is often produced illegally in clandestine laboratories using over-the-counter medications containing pseudoephedrine or ephedrine as a precursor. Methamphetamine abuse can have severe and long-lasting effects on the brain and body, including addiction, impaired judgment, and physical and mental health problems.

InChI:InChI=1/C9H11NO/c1-10-7-9(11)8-5-3-2-4-6-8/h2-6,10H,7H2,1H3

Upstream product

• 100-42-5 styrene 
• 123-39-7 N-Methylformamide 
• 25808-30-4 2-(methylamino)acetonitrile hydrochloride 
• 71-43-2 benzene 
• 593-51-1 methylamine hydrochloride 
• 70-11-1 α-bromoacetophenone 
• 74879-77-9 [(2S,3S)-1-Methyl-3-(3-nitro-phenyl)-aziridin-2-yl]-phenyl-methanone 
• 74300-26-8 [(2R,3R)-3-(4-Bromo-phenyl)-1-methyl-aziridin-2-yl]-phenyl-methanone 
• 74879-75-7 [(2R,3R)-3-(4-Chloro-phenyl)-1-methyl-aziridin-2-yl]-phenyl-methanone 
• 74300-28-0 ((2R,3R)-1-Methyl-3-p-tolyl-aziridin-2-yl)-phenyl-methanone 
• 6476-40-0 cis-1-methyl-2-benzoyl-3-phenylaziridine 
• 74-89-5 methylamine 
• 98-86-2 acetophenone 
• 124-40-3 dimethyl amine 

Downstream Products

• 56157-01-8 N,4-dimethyl-N-(2-oxo-2-phenylethyl)benzenesulfonamide 
• 35746-37-3 N-methyl-N-(2-oxo-2-phenylethyl)acetamide 
• 65058-52-8 N-methyl (S)-2-hydroxy-2-phenylethylamine 
• 495-42-1 (-)-Halostachine 
• 114376-13-5 (3S,4R,5R)-clausenamidone 
• 65-85-0 benzoic acid 
• 68579-60-2 2-(methylamino)-1-phenylethanol 
• 112698-39-2 2-amino-6--5-nitro-4(3H)-pyrimidinone 

Relevant articles and documents

A METAL FREE PROCESS FOR THE PREPARATION OF ALPHA-SUBSTITUTED CARBONYL COMPOUNDS FROM ALKENES

The present invention discloses a novel metal free process for the regioselective synthesis of α-substituted carbonyl compounds of formula I from alkene, X is selected from the following compounds (A, B).

Superelectrophilic chemistry of amino-nitriles and related substrates

The superacid-promoted Houben/Hoesch reactions of amino-nitriles and related compounds have been studied. The nitriles form dicationic electrophiles and react with benzene in fair to good yields (12-95%). The intermediate iminium ions may also be reduced to the benzylic amines by NaBH4 or H 2.

Nitrogen mustard analogs. β-Halogeno-, β-alkoxy- and β-acetoxy- β-phenylethylamine derivatives

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