35604-67-2 Usage
Description
2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride is an organic compound with the chemical formula C12H20ClNO3. It is a derivative of morpholine, an ether-modified phenol, and a hydrochloride salt. 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride exhibits unique chemical and physical properties, making it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride is used as an antidepressant for the treatment of depression. It is a research-useful chemical that has been found to exhibit antidepressant properties, providing a potential therapeutic option for individuals suffering from depressive disorders.
Used in Chemical Research:
In the field of chemical research, 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride serves as a valuable chemical intermediate. Its unique structure allows for further modification and synthesis of new compounds with potential applications in various industries, including pharmaceuticals, materials science, and agrochemicals.
Used in Material Science:
2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride can be utilized as a component in the development of new materials with specific properties. Its ability to form hydrogen bonds and interact with other molecules makes it a promising candidate for use in the creation of advanced materials with tailored characteristics, such as improved solubility, stability, or reactivity.
Used in Agrochemical Industry:
In the agrochemical industry, 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride may be employed as an active ingredient or a precursor in the synthesis of pesticides, herbicides, or other crop protection agents. Its unique chemical properties could contribute to the development of more effective and environmentally friendly agrochemicals.
Originator
Vivalan,I.C.I. ,UK,1974
Manufacturing Process
2-Ethoxyphenol is first reacted with epichlorohydrin to give 1,2-epoxy-3-(o-
ethoxyphenoxy)-propane.
A mixture of crude (83%) 1,2-epoxy-3-(o-ethoxyphenoxy)propane (19.4
grams), 70.5 grams 2-aminoethyl hydrogen sulfate, 40.0 grams sodium
hydroxide, 400 ml ethanol and 200 ml water is stirred at 60°C for 18 hours
and is then evaporated to dryness. The residue is dissolved in 200 ml water
and the mixture is extracted three times with 150 ml of diethyl ether each
time. The combined extracts are dried over magnesium sulfate and
evaporated to dryness, The crude product (21.5 grams) is dissolved in
isopropanol (20 ml), 10.5 ml concentrated aqueous hydrochloric acid and 75
ml ethyl acetate are added and the mixture is cooled. The mixture is filtered
and there is thus obtained as solid product 2-(o-ethoxyphenoxymethyl)
morpholine hydrochloride, MP 179° to 182°C (8.6 grams; 38% yield based on
total epoxide used), according to US Patent 3,712,890.
Therapeutic Function
Psychotropic
Check Digit Verification of cas no
The CAS Registry Mumber 35604-67-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,6,0 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 35604-67:
(7*3)+(6*5)+(5*6)+(4*0)+(3*4)+(2*6)+(1*7)=112
112 % 10 = 2
So 35604-67-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H19NO3.ClH/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11;/h3-6,11,14H,2,7-10H2,1H3;1H
35604-67-2Relevant articles and documents
METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF
-
, (2011/10/19)
Provided here are methods of manufacture of viloxazine and its various salts, as well as viloxazine-related compounds, such as novel intermediate reaction products and polymorphs thereof. In particular, the methods provide a substantially pure API of viloxazine HCl while avoiding undesirable impurities. The methods further provide for separating, identifying, and characterizing novel polymorphs of viloxazine. Further provided are methods for synthesis and identification and characterization of novel intermediates of viloxazine, as well as for some important metabolites and precursors of metabolites of viloxazine.
