5296-35-5

Basic information

• Product Name: 2-[(2-ethoxyphenoxy)methyl]oxirane
• Synonyms: 2-[(2-ethoxyphenoxy)methyl]oxirane;1-(2-Ethoxyphenoxy)-2,3-epoxypropane;2-Ethoxyphenyl Glycidyl Ether
• CAS NO: 5296-35-5
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.22706
• Product Categories: Aromatics;Intermediates
• Mol File: 5296-35-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 45 °C
• Boiling Point: 122 °C(Press: 4 Torr)
• Appearance: /
• Density: 1.114±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Dichloromethane, Ethyl Acetate
• CAS DataBase Reference: 2-[(2-ethoxyphenoxy)methyl]oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2-ethoxyphenoxy)methyl]oxirane(5296-35-5)
• EPA Substance Registry System: 2-[(2-ethoxyphenoxy)methyl]oxirane(5296-35-5)

Safety Data

• Hazardous Substances Data: 5296-35-5(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

Uses

Intermediate in the preparation of Morpholine derivatives.

Upstream product

• 94-71-3 2-Ethoxyphenol 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 106-89-8 epichlorohydrin 

Downstream Products

• 1338700-16-5 C₂₀H₂₇NO₄ 
• 46817-91-8 viloxazine 
• 35604-67-2 2-[(2-Ethoxyphenoxy)-methyl]morpholine hydrochloride 
• 47374-79-8 (+/-)-4-benzyl-2-(2-ethoxyphenoxymethyl)morpholine 
• 14754-63-3 3-(2-Ethoxy-phenoxy)-1-methylamino-propanol-⁽²⁾ 
• 14754-58-6 1-Isopropylamino-2-hydroxypropyl-1'-ethoxyphenylether 
• 139003-93-3 N,N'-Dibenzylfalirytmin dihydrochlorid 

Relevant articles and documents

Substituted diaryl compound and preparation method and application thereof

The invention relates to the field of medicinal chemistry, in particular to a substituted diaryl compound (I). The preparation method comprises the following steps: medicine preparation and medical application thereof. Test results show that the substituted diaryl compound has a good inhibition effect on human lung cancer (A549), human ovarian cancer (SKOV3), human melanoma (A375) and human colon cancer (LOVO) cells. Formula (I):

METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF

Provided here are methods of manufacture of viloxazine and its various salts, as well as viloxazine-related compounds, such as novel intermediate reaction products and polymorphs thereof. In particular, the methods provide a substantially pure API of viloxazine HCl while avoiding undesirable impurities. The methods further provide for separating, identifying, and characterizing novel polymorphs of viloxazine. Further provided are methods for synthesis and identification and characterization of novel intermediates of viloxazine, as well as for some important metabolites and precursors of metabolites of viloxazine.