35677-88-4

Basic information

• Product Name: N-Carbobenzoxy-L-homoserine
• Synonyms: Cbz-hse-OH;N-(Benzyloxycarbonyl)-L-homoserine;N-Carbobenzoxy-L-homoserine;Cbz-L-Homoserine;Cbz-Homoserine;L-HoMoserine, N-[(phenylMethoxy)carbonyl]-;2-CarboxyaMino-4-hydroxybutyric acid, N-benzyl Ester;Cbz-HoMoser Cbz-HoMoserine Cbz-Hse
• CAS NO: 35677-88-4
• Molecular Formula: C₁₂H₁₅NO₅
• Molecular Weight: 253.25
• Product Categories: Amino Acids & Derivatives;Aromatics
• Mol File: 35677-88-4.mol
• Article Data: 23

Chemical Properties

• Melting Point: 100-101 °C
• Boiling Point: 519.917 °C at 760 mmHg
• Flash Point: 268.236 °C
• Appearance: /
• Density: 1.311
• Vapor Pressure: 1.23E-11mmHg at 25°C
• Refractive Index: 1.563
• Storage Temp.: 2-8°C
• PKA: 3.85±0.10(Predicted)
• CAS DataBase Reference: N-Carbobenzoxy-L-homoserine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Carbobenzoxy-L-homoserine(35677-88-4)
• EPA Substance Registry System: N-Carbobenzoxy-L-homoserine(35677-88-4)

Safety Data

• Hazardous Substances Data: 35677-88-4(Hazardous Substances Data)

Usage

Uses

N-Carbobenzoxy-L-homoserine (cas# 35677-88-4) is a compound useful in organic synthesis.

InChI:InChI=1/C12H15NO5/c14-7-6-10(11(15)16)13-12(17)18-8-9-4-2-1-3-5-9/h1-5,10,14H,6-8H2,(H,13,17)(H,15,16)/t10-/m0/s1

Upstream product

• 35677-89-5 benzyl (3S)-2-oxotetrahydro-3-furanylcarbamate 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 672-15-1 L-homoserine 
• 39256-89-8 N-Benzyloxycarbonyl-L-asparaginsaeure-β-aethylester 
• 501-53-1 benzyl chloroformate 
• 498-19-1 L-(-)-homoserine 

Downstream Products

• 116506-83-3 Caesium; 2-benzyloxycarbonylamino-4-trityloxy-butyrate 
• 314728-04-6 (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester 
• 162537-22-6 (S )-2-(((benzyloxy)carbonyl)amino)-4-((tert-butyldimethylsilyl)oxy)butanoic acid 
• 634587-01-2 (3S,4S,5R)-1-O-(tert-butyldimethylsilyl)-3-[(benzyloxycarbonyl)amino]-4,5-nonadecanediol 
• 634587-04-5 (3S,4R,5S)-1-O-(tert-butyldimethylsilyl)-3-[(benzyloxycarbonyl)amino]-4,5-nonadecanediol 
• 95656-90-9 (S)-2-Benzyloxycarbonylamino-4-bromo-butyric acid benzyl ester 
• 15159-67-8 (2S)-2-benzyloxycarbonylamino-4-bromo-butyric acid methyl ester 
• 1159501-78-6 (S)-2-benzyloxycarbonylamino-4-(diethoxy-phosphoryl)-butyric acid methyl ester 
• 120286-25-1 (2S)-2-{[(benzyloxy)carbonyl]amino}-4-(diethoxyphosphoryl)butanoic acid 
• 58578-43-1 (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid dicyclohexylamine salt 

Relevant articles and documents

Synthesis of α-PNA containing a functionalized triazine as nucleobase analogue

The design of artificial structures such as Peptide Nucleic Acids (PNAs) capable of recognizing nucleic acids has attracted much attention. We report herein the design of l-homoserine derivatives bearing diaminotriazine groups as artificial nucleobase cap

NOVEL COMPOUNDS AND METHODS OF USE TREATING FRUCTOSE-RELATED DISORDERS OR DISEASES

Disclosed herein are novel compounds that inhibit fructokinase (KHK or ketohexokinase) and the downstream metabolic effects mediated by fructose metabolism. Fructokinase inhibitors specifically block the metabolism of both dietary and endogenous fructose

MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS

Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.