95656-90-9

Basic information

• Product Name: Butanoic acid, 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]-, phenylmethyl ester, (2S)-
• CAS NO: 95656-90-9
• Molecular Formula: C19H20BrNO4
• Molecular Weight: 406.276
• Mol File: 95656-90-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]-, phenylmethyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]-, phenylmethyl ester, (2S)-(95656-90-9)
• EPA Substance Registry System: Butanoic acid, 4-bromo-2-[[(phenylmethoxy)carbonyl]amino]-, phenylmethyl ester, (2S)-(95656-90-9)

Safety Data

• Hazardous Substances Data: 95656-90-9(Hazardous Substances Data)

Upstream product

• 58578-44-2 benzyl L-2-<(carbobenzxyloxy)amino>-4-hydroxybutyrate 
• 501-53-1 benzyl chloroformate 
• 35677-88-4 N-benzyloxycarbonyl-(L)-homoserine 
• 3705-42-8 Cbz-(L)-Glu-OBn 

Relevant articles and documents

Diaminodiacid bridge improves enzymatic and in vivo inhibitory activity of peptide CPI-1 against botulinum toxin serotype A

The replacement of the disulfide bridge of CPI-1, a peptide inhibitor of light chain of Botulinum toxin serotype A, with the thioether-containing and biscarba-containing diaminodiacid bridge leads to a significant decrease in the degradation by trypsin and increase in the detoxification activity in vivo, the addition of hydrophobic or positive amino acid at C-terminus of modified peptides further improves the inhibitory activity.

MANIPULATION OF THE CARBOXYL GROUPS OF α-AMINO-ACIDS AND PEPTIDES USING RADICAL CHEMISTRY BASED ON ESTERS OF N-HYDROXY-2-THIOPYRIDONE

Photolysis of α-amino-acid or peptide esters derived from N-hydroxy-2-thiopyridone in the presence of t-butylthiol affords the expected decarboxylation products in good yield.The reaction can be applied to the α-carboxyl or to the side chain carboxyl of g