35782-30-0Relevant articles and documents
The facile route to stereodefined alkenyl-substituted pyrimidines
Tan, Jiuqing,Chang, Jianhua,Deng, Minzhi
, p. 3773 - 3783 (2004)
The Suzuki-Miyaura type cross-coupling reactions of various chloropyrimidines with Stereodefined alkenylboronic acids giving the corresponding alkenyl-substituted pyrimidines were studied. The experiments discovered that the reaction is stereospecific and
Aryl-Nickel-Catalyzed Benzylic Dehydrogenation of Electron-Deficient Heteroarenes
Zhang, Pengpeng,Huang, David,Newhouse, Timothy R.
supporting information, p. 1757 - 1762 (2020/02/04)
This manuscript describes the first practical benzylic dehydrogenation of electron-deficient heteroarenes, including pyridines, pyrazines, pyrimidines, pyridazines, and triazines. This transformation allows for the efficient benzylic oxidation of heteroarenes to afford heterocyclic styrenes by the action of nickel catalysis paired with an unconventional bromothiophene oxidant.
Stannylation in the Electrophilic 2- and 4/6-Pyrimidine Position and the Use of Stannylpyrimidines in Coupling and Tin-Lithium Exchange Reactions
Sandosham, Jessie,Undheim, Kjell
, p. 275 - 284 (2007/10/02)
2-Stannylpyrimidines have been prepared by stannyl anion substitution in 2-chloropyrimidines.Stannylation in the 4-position was via the iodo-derivative or via the 4-lithio derivative and lithium-tin transmetallation.Tin-lithium exchange in the 2-position