358788-86-0

Basic information

• Product Name: 4-Anilino-5-bromo-2-{4-{N-[2-(diethylamino)ethyl]carbamoyl}anilino}pyrimidine
• CAS NO: 358788-86-0
• Molecular Weight: 483.411
• Mol File: 358788-86-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Anilino-5-bromo-2-{4-{N-[2-(diethylamino)ethyl]carbamoyl}anilino}pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Anilino-5-bromo-2-{4-{N-[2-(diethylamino)ethyl]carbamoyl}anilino}pyrimidine(358788-86-0)
• EPA Substance Registry System: 4-Anilino-5-bromo-2-{4-{N-[2-(diethylamino)ethyl]carbamoyl}anilino}pyrimidine(358788-86-0)

Safety Data

• Hazardous Substances Data: 358788-86-0(Hazardous Substances Data)

Upstream product

• 51-06-9 4-amino-N-(2-diethylaminoethyl)benzamide 
• 280581-50-2 5-bromo-2-chloro-N-phenylpyrimidin-4-amine 

Relevant articles and documents

2,4-Di(hetero-)arylamino (oxy)-5-substituted pyrimidines as antineoplastic agents

Pyrimidine derivatives of the formula (I), wherein: Q1 and Q2 are independently selected from aryl or carbon linked heteroaryl optionally substituted as defined within; and one or both Q1 and Q2 are substituted on a ring carbon by one substituent of the formula (Ia) or (Ia′), wherein: Y, Z, n, m, Q3, G, R1, are as defined within; and pharmaceutically acceptable salts and in in vivo hydrolyzable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.