280581-50-2 Usage
General Description
5-Bromo-2-chloro-N-phenyl-4-pyrimidinamine is a chemical compound used in the field of organic chemistry. It is a pyrimidine derivative that contains bromine and chlorine substituents on the pyrimidine ring, as well as a phenyl group attached to the nitrogen atom. 5-Bromo-2-chloro-N-phenyl-4-pyrimidinamine has potential applications in the pharmaceutical industry, particularly in the development of new drugs or therapeutic agents. Its unique structure and chemical properties make it a valuable building block for the synthesis of complex organic molecules. Additionally, its properties may also have potential uses in biological and medical research, making it a compound of interest for scientists and researchers in various fields. Overall, 5-Bromo-2-chloro-N-phenyl-4-pyrimidinamine is a versatile and important chemical compound with various potential applications in the chemical, pharmaceutical, and biomedical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 280581-50-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,0,5,8 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 280581-50:
(8*2)+(7*8)+(6*0)+(5*5)+(4*8)+(3*1)+(2*5)+(1*0)=142
142 % 10 = 2
So 280581-50-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H7BrClN3/c11-8-6-13-10(12)15-9(8)14-7-4-2-1-3-5-7/h1-6H,(H,13,14,15)
280581-50-2Relevant articles and documents
Structure-activity relationship of 7-aryl-2-anilino-pyrrolopyrimidines as Mer and Axl tyrosine kinase inhibitors
Chung, Shin Hyuck,Park, Jiwon,Lee, Jung Wuk,Song, Jiho,Jung, Danbee,Min, Kyung Hoon
, p. 1822 - 1833 (2020/10/02)
The TAM (Axl, Mer, and Tyro3) family is implicated in the survival and chemoresistance of tumours and has emerged as a potential therapeutic target. A novel series of 7-aryl-2-anilino-pyrrolopyrimidines were identified as potent Axl/Mer tyrosine kinase in
SULPHIMIDES AS PROTEIN KINASE INHIBITORS
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Page/Page column 22; 23, (2008/06/13)
The invention relates to sulphimides as protein kinase inhibitors of the general formula I
Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 2: Identification and optimisation of substituted 2,4-bis anilino pyrimidines
Breault, Gloria A.,Ellston, Rebecca P. A.,Green, Stephen,James, S. Russell,Jewsbury, Philip J.,Midgley, Catherine J.,Pauptit, Richard A.,Minshull, Claire A.,Tucker, Julie A.,Pease, J. Elizabeth
, p. 2961 - 2966 (2007/10/03)
Through chemical modification and X-ray crystallography we identified the 2,4-bis anilino pyrimidines as potent inhibitors of CDK4. Herein, we describe the optimisation of this series.
