3590-37-2

Basic information

• Product Name: ETHYL 3-NITROPROPANOATE
• Synonyms: ETHYL 3-NITROPROPANOATE;3-Nitropropanoic acid ethyl ester;Ethyl 3-nitropropionate;Propanoic acid,3-nitro-, ethyl ester
• CAS NO: 3590-37-2
• Molecular Formula: C₅H₉NO₄
• Molecular Weight: 147.13
• Mol File: 3590-37-2.mol
• Article Data: 14

Chemical Properties

• Melting Point: 160-165℃
• Boiling Point: 223℃
• Flash Point: 106℃
• Appearance: /
• Density: 1.155
• Vapor Pressure: 0.097mmHg at 25°C
• Refractive Index: 1.432
• PKA: 7.70±0.29(Predicted)
• CAS DataBase Reference: ETHYL 3-NITROPROPANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-NITROPROPANOATE(3590-37-2)
• EPA Substance Registry System: ETHYL 3-NITROPROPANOATE(3590-37-2)

Safety Data

• Hazardous Substances Data: 3590-37-2(Hazardous Substances Data)

Usage

General Description

Ethyl 3-nitropropanoate is a chemical compound with the molecular formula C5H9NO4. It is an ester, meaning it is derived from the reaction between ethanol and 3-nitropropanoic acid. ETHYL 3-NITROPROPANOATE is commonly used in organic synthesis as a reagent for the preparation of various other organic compounds. It is a colorless liquid with a fruity odor and is known to be highly flammable. Ethyl 3-nitropropanoate is also used in the production of pharmaceuticals and as a flavoring agent in the food industry due to its fruity aroma. However, it is important to handle this chemical with care, as it is known to be toxic and can cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C5H9NO4/c1-2-10-5(7)3-4-6(8)9/h2-4H2,1H3

Upstream product

• 1193-10-8 3-methyl-2,5-dihydrothiophen-1,1-dioxide 
• 5941-50-4 ethyl β-nitroacrylate 
• 504-88-1 3-nitropropionic acid 
• 1851-84-9 ethyl 2-hydroxy-3-nitropropanoate 
• 5941-50-4 (E)-ethyl 3-nitroacrylate 
• 64-17-5 ethanol 
• 27374-25-0 [(1-Ethoxycyclopropyl)oxy]trimethylsilane 
• 122876-02-2 ethyl 3-nitro-3-(phenylsulfonyl)propionate 
• 539-74-2 Ethyl 3-bromopropionate 
• 6414-69-3 ethyl 3-iodopropanoate 

Downstream Products

• 79852-93-0 3-Nitro-3-(phenyl-hydrazono)-propionic acid ethyl ester 
• 77802-23-4 3-Nitro-2-naphthoesaeure-aethylester 
• 73428-03-2 3-Nitro-2-naphthoesaeure 
• 114957-76-5 diethyl 2-acetyl-4-(5-phenyl-3-isoxazolyl)-3-<2-(trifluoromethyl)phenyl>pentanedioate 
• 114978-18-6 (2Z,3α,4β)-(+/-)-diethyl 1,2,3,4-tetrahydro-6-methyl-2-(2-oxo-2-phenylethylidene)-4-<2-(trifluoromethyl)phenyl>-3,5-pyridinedicarboxylate 
• 114957-77-6 2-Acetyl-3-phenyl-4-(5-phenyl-isoxazol-3-yl)-pentanedioic acid diethyl ester 
• 114957-70-9 (3S,4R)-6-Methyl-2-[2-oxo-2-phenyl-eth-(Z)-ylidene]-4-phenyl-1,2,3,4-tetrahydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 348618-36-0 4-(4-chloro-5-methoxy-2-methylanilino)-8-methoxy-7-[2-(4-morpholinyl)ethoxy]benzo[g]quinoline-3-carbonitrile 

Relevant articles and documents

Pyrrolo[2,1-c][1,4]naphthodiazepine Linked Piperazine Compounds and a Process for the Preparation Thereof

The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R=R′=(Formula II). n=1-9 and R″=methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl

PYRROLO [2,1-C]1,4]NAPHTHODIAZEPINE LINKED PIPERAZINE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF

The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R= R'= (Formula II). n=1-9 and R''= methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl

Diastereoselective synthesis of 1,3,5- Trisubstituted 4-nitropyrrolidin-2- ones via a nitro-mannich/lactamization cascade

A versatile one-pot nitro-Mannich/lactamization cascade for the direct synthesis of 1,3,5-trisubstituted 4-nitropyrrolidin-2-ones has been developed. The reaction is easy to perform and broad in scope, and high levels of diastereoselectivity can be achiev