35959-11-6Relevant articles and documents
Markley,Sando,Hendricks
, p. 641,651, 652 (1938)
DDQ-promoted dehydrogenation from natural rigid polycyclic acids or flexible alkyl acids to generate lactones by a radical ion mechanism
Ding, Ye,Huang, Zhangjian,Yin, Jian,Lai, Yisheng,Zhang, Shibo,Zhang, Zhiguo,Fang, Lei,Peng, Sixun,Zhang, Yihua
supporting information; experimental part, p. 9495 - 9497 (2011/10/31)
A novel and facile DDQ-mediated dehydrogenation from natural rigid polycyclic acids or flexible alkyl acids to generate lactones is described. The formation of lactones proceeds by a radical ion mechanism, which has been established by DPPH?-mediated chemical identification, ESR spectroscopy and an enol intermediate trapping.
Oxyfunctionalization products of terpenoids with dimethyldioxirane and their biological activity
Ogawa, Shoujiro,Hosoi, Keiji,Ikeda, Noriaki,Makino, Mitsuko,Fujimoto, Yasuo,Iida, Takashi
, p. 247 - 250 (2007/10/03)
Oxyfunctionalization of the bioactive terpenoids, ursolic acid acetate (1), oleanolic acid acetate (5), lupeol acetate (12), and kaurenic acid (17), with dimethyldioxirane (DMDO) was investigated. Treatment of the terpenoids with DMDO under mild conditions afforded a variety of oxidation and oxydegradation products to yield naturally occurring and/or novel compounds in one step. After chromatographic separation, the structures of the individual isolated products were determined using spectroscopic methods including several homonuclear ( 1H-1H) and heteronuclear (1H-13C) shift-correlated 2D-NMR techniques. The inhibitory activity of the terpenoid derivatives against α-glucosidase was investigated and compounds 1, 3, 7, and 9 were found to exhibit potent activity.
