35998-30-2

Basic information

• Product Name: 2(3H)-Furanone, dihydro-3-(phenylthio)-
• Synonyms: 2-phenylthiobutyrolactone;3-phenylsulfanyl-dihydro-furan-2-one;3-(phenylsulfanyl)-3,4-dihydrofuran-2-one;2(3H)-Furanone,dihydro-3-(phenylthio)
• CAS NO: 35998-30-2
• Molecular Formula: C10H10O2S
• Molecular Weight: 194.254
• Mol File: 35998-30-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 130-140 °C(Press: 0.8 Torr)
• Density: 1.25±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2(3H)-Furanone, dihydro-3-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone, dihydro-3-(phenylthio)-(35998-30-2)
• EPA Substance Registry System: 2(3H)-Furanone, dihydro-3-(phenylthio)-(35998-30-2)

Safety Data

• Hazardous Substances Data: 35998-30-2(Hazardous Substances Data)

Usage

Structure

Heterocyclic organic compound with a furanone ring and a phenylthio group

Usage

Synthesis of pharmaceuticals, agrochemicals, flavor and fragrance industry

Odor

Characteristic sweet, fruity odor

Application

Flavoring agent in food products

Biological activity

Potential for medicinal chemistry research

Health and environmental concerns

Potential toxicity and persistence

Upstream product

• 882-33-7 diphenyldisulfane 
• 21034-21-9 α-benzoyl-γ-butyrolactone 
• 931-59-9 benzenesulfenyl chloride 
• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 5061-21-2 α-bromo-γ-butyrolactone 
• 2973-86-6 lithium thiophenoxide 
• 108-98-5 thiophenol 
• 57340-80-4 thallium thiophenoxide 
• 96-48-0 4-butanolide 
• 930-69-8 sodium thiophenolate 

Downstream Products

• 62675-47-2 α-chloro-α-(phenylthio)-γ-butyrolactone 
• 949562-88-3 acetic acid 2-(2-methyl-6-oxocyclohex-1-enyl)-1-(2-oxo-3-phenylsulfanyl-3,4-dihydrofuran-3-yl)ethyl ester 
• 109765-89-1 4,5-dihydro-3-(1-hydroxybutyl)-3-phenylthio-3H-furan-2-one 
• 342624-00-4 methyl 1-(phenylthio)cyclopropanecarboxylate 
• 1280709-98-9 5-(2-nitro-1-phenylethyl)-3-phenylthiofuran-2(5H)-one 
• 1134582-49-2 C₁₅H₁₇IO₂S 
• 82111-93-1 (S)-3-[2-((1S,2R)-2-Hydroxy-2,6,6-trimethyl-cyclohexyl)-acetyl]-3-phenylsulfanyl-dihydro-furan-2-one 
• 76232-18-3 (S)-3-[1-Hydroxy-2-((1S,2R)-2-hydroxy-2,6,6-trimethyl-cyclohexyl)-ethyl]-3-phenylsulfanyl-dihydro-furan-2-one 
• 82111-92-0 (S)-3-[2-((1S,2S)-2-Hydroxy-2-methyl-cyclohexyl)-acetyl]-3-phenylsulfanyl-dihydro-furan-2-one 
• 82111-91-9 (S)-3-[1-Hydroxy-2-((1R,2R)-2-hydroxy-2-methyl-cyclohexyl)-ethyl]-3-phenylsulfanyl-dihydro-furan-2-one 

Relevant articles and documents

Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions

We report a biocatalytic platform of engineered cytochrome P450 enzymes to carry out carbene-transfer reactions using a lactone-based carbene precursor. By simply altering the heme-ligating residue, we obtained two enzymes that catalyze olefin cyclopropan

Method for synthesizing 4-vinyl-2(5H)-furanone

The invention discloses a method for synthesizing 4-vinyl-2(5H)-furanone. The method comprises the following steps: step (1) taking and adding metal sodium into methanol, dripping thiophenol into themethanol, and then continuously adding alpha-bromo-gamma

Synthesis and in vitro antitumor activity of new butenolide-containing dithiocarbamates

Three series of butenolide-containing dithiocarbamates were designed and synthesized. Their anti-tumor activity in vitro was evaluated. Among them compound I-14 exhibited broad spectrum anti-cancer activity against five human cancer cell lines with IC50 30 μM. Structure-activity relationship analysis showed that the introduction of dithiocarbamate side chains on the C-3 position of butenolide was crucial for anti-tumor activity.