367527-75-1

Basic information

• Product Name: (2'-(tert-butyldimethyl)silyloxy)-7-chloromethyloxycarbonylpaclitaxel
• Synonyms: (2'-(tert-butyldimethyl)silyloxy)-7-chloromethyloxycarbonylpaclitaxel
• CAS NO: 367527-75-1
• Molecular Weight: 1060.66
• Mol File: 367527-75-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2'-(tert-butyldimethyl)silyloxy)-7-chloromethyloxycarbonylpaclitaxel(CAS DataBase Reference)
• NIST Chemistry Reference: (2'-(tert-butyldimethyl)silyloxy)-7-chloromethyloxycarbonylpaclitaxel(367527-75-1)
• EPA Substance Registry System: (2'-(tert-butyldimethyl)silyloxy)-7-chloromethyloxycarbonylpaclitaxel(367527-75-1)

Safety Data

• Hazardous Substances Data: 367527-75-1(Hazardous Substances Data)

Upstream product

• 22128-62-7 carbonochloridic acid, chloromethyl ester 
• 114655-02-6 2'-O-(tert-butyldimethylsilyl)paclitaxel 
• 1151989-07-9 C₆₀H₆₀N₂O₁₆S₂ 

Downstream Products

• 367527-76-2 7-chloromethyloxycarbonylpaclitaxel 
• 1151990-16-7 (7-O-paclitaxelcarbonyloxy)methyl 5-(1,2-dithiolan-3-yl)pentanoate 

Relevant articles and documents

Synthesis and Evaluation of Paclitaxel-Loaded Gold Nanoparticles for Tumor-Targeted Drug Delivery

The synthesis of a series of thiolated paclitaxel analogs is described as part of a novel nanomedicine program aimed at developing formulations of paclitaxel that will bind to gold nanoparticles for tumor targeted drug delivery. Preliminary evaluation of the new nanomedicine composed of 27 nm gold nanoparticles, tumor necrosis factor alpha (TNFα), thiolated polyethylene glycol (PEG-thiol), and one of several thiolated paclitaxel analogs is presented.