368421-81-2Relevant articles and documents
Sequential nucleophilic addition/1,2-rearrangement of N-iminolactam: A ring-contractive strategy for the synthesis of 2-acyl pyrrolidines
Kido, Yusaku,Kobori, Yukiko,Matsumoto, Yuki,Orihara, Kotomi,Takeda, Norihiko,Ueda, Masafumi,Yasui, Motohiro
supporting information, (2021/06/07)
A sequential nucleophilic addition/ring contraction of α-bromo N-iminolactam with organometallic reagents for the synthesis of 2-acyl pyrrolidines has been developed. The reaction allows facial construction of 2-acyl pyrrolidines incorporating not only ar
One-Pot Synthesis of Substituted Trifluoromethylated 2,3-Dihydro-1H-imidazoles
Deutsch, Amrei,Jessen, Christoph,Deutsch, Carl,Karaghiosoff, Konstantin,Hoffmann-R?der, Anja
supporting information, p. 3474 - 3477 (2016/07/26)
An operationally simple one-pot reaction for the preparation of a novel class of racemic trifluoromethylated 2,3-dihydro-1H-imidazoles derived from electron-poor N,O-acetals and aryl Grignard reagents is described. In addition, access to highly functional
Method of preparing organomagnesium compounds
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Figure 3, (2010/02/14)
The present invention is directed to a reagent for use in the preparation of organomagnesium compounds as well as to a method of preparing such organomagnesium compounds. The present invention furthermore provides a method of preparing functionalized or unfunctionalized organic compounds as well as the use of the reagents of the present invention in the preparation of organometallic compounds and their reaction with electrophiles. Finally, the present invention is directed to the use of lithium salts - LiY in the preparation of organometallic compounds and their reactions with electrophiles and to an organometallic compound which is obtainable by the disclosed method.