36866-66-7Relevant articles and documents
Cobalt-catalysed addition of allylidene dipivalate to aldehydes. A formal homoaldol condensation
Lombardo, Marco,Licciulli, Sebastiano,Pasi, Filippo,Angelici, Gaetano,Trombini, Claudio
, p. 2015 - 2018 (2005)
A Co(I)-catalysed condensation of allylidene dipivalate with aldehydes to give (Z)-4-hydroxybut-1-enyl pivalates in 62 to 87% isolated yields, is reported. Reactions are run in acetonitrile at 0 or 25°C depending on the nature of the aldehyde, and exploit
Selective mono addition of aryllithiums to dialdehydes by micromixing
Nagaki, Aiichiro,Yamashita, Hiroki,Takahashi, Yusuke,Ishiuchi, Satoshi,Imai, Keita,Yoshida, Jun-Ichi
supporting information, p. 71 - 73 (2018/01/26)
Micromixing enables highly selective mono addition of aryllithiums to dialdehydes. Because the unchanged formyl group in the products can be used for further transformations, the present approach serves as a powerful method for protecting-group-free synthesis.
Unusual aluminum hydride-mediated reduction of N-(γ- or δ-oxoacyl)oxazolidinone
Yamaguchi, Jun-Ichi,Asano, Mayuko,Udono, Youko
supporting information, p. 371 - 372 (2014/03/21)
Reduction of N-(γ-oxoacyl)oxazolidinone with a borohydride reagent, such as NaBH4 or LiBEt3H, resulted in formation of the corresponding lactone or lactol. In contrast, when an aluminum hydride reagent was used instead of a borohydride reagent, reduction of N-(γ- or δ-oxoacyl)oxazolidinone proceeded unexpectedly to give not the corresponding lactone or lactol, but a tetrahydrofuran or tetrahydropyran derivative, respectively, containing an oxazolidino group.
Microwave-assisted domino hydroformylation without syngas
Cini, Elena,Airiau, Etienne,Girard, Nicolas,Mann, André,Salvadori, Jessica,Taddei, Maurizio
experimental part, p. 199 - 202 (2011/03/22)
Hydroformylation is a powerful reaction that has suffered for some negative prejudices related to the use of gaseous H2 and CO. Now it is possible to carry out hydroformylation and different cyclohydrocarbonylations, even on complex substrates, using aqueous formalin as H2 and CO surrogate in few minutes under microwave irradiation. The catalytic system developed by Morimoto (Rh/BINAP for decomposition of formaldehyde and Rh/Xantphos for hydroformylation) is compatible with microwave dielectric heating and with complex substrates containing ligand atoms allowing rapid domino hydroformylation cyclization reactions without using the external supply of gaseous H2 and CO (gas cylinder) and without any particular safety limitation or device. Georg Thieme Verlag Stuttgart.