36980-13-9

Basic information

• Product Name: 1H-Pyrazolo[3,4-b]pyridine-5-carbonyl chloride, 4-chloro-1-ethyl-3-methyl-
• CAS NO: 36980-13-9
• Molecular Formula: C10H9Cl2N3O
• Molecular Weight: 258.107
• Mol File: 36980-13-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazolo[3,4-b]pyridine-5-carbonyl chloride, 4-chloro-1-ethyl-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-b]pyridine-5-carbonyl chloride, 4-chloro-1-ethyl-3-methyl-(36980-13-9)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-b]pyridine-5-carbonyl chloride, 4-chloro-1-ethyl-3-methyl-(36980-13-9)

Safety Data

• Hazardous Substances Data: 36980-13-9(Hazardous Substances Data)

Upstream product

• 34970-33-7 1-ethyl-3-methyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 
• 37801-47-1 4-chloro-1-ethyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester 
• 3524-33-2 1-ethyl-3-methyl-1H-pyrazol-5-amine 
• 26824-00-0 (2-ethyl-5-methyl-2H-pyrazol-3-ylaminomethylene)-malonic acid diethyl ester 
• 851520-85-9 4-chloro-1-ethyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 

Relevant articles and documents

Discovery of new orally active phosphodiesterase (PDE4) inhibitors

A series of 4-anilinopyrazolopyridine derivatives were synthesized and biologically evaluated as inhibitors of phosphodiesterase (PDE4). Chemical modification of 3, a structurally new chemical lead that was found in our in-house library, was focused on 1- and 3-substituents. Full details of the discovery of a new orally active chemical lead 5 are presented. Structure-activity relationship data, pharmacological evaluation, and the subtype selectivity study are also presented.