3779-03-1 Usage
Description
9-METHOXY-2,3-DIHYDROFURO[3,2-G]COUMARIN is a furocoumarin derivative with potential applications in various fields due to its unique chemical properties and biological activities.
Uses
Used in Insect Control:
9-METHOXY-2,3-DIHYDROFURO[3,2-G]COUMARIN is used as an insect antifeeding agent for its ability to deter insects from feeding on treated plants. This property makes it a valuable tool in agriculture for protecting crops from insect damage.
Used in Pharmaceutical Industry:
9-METHOXY-2,3-DIHYDROFURO[3,2-G]COUMARIN is used as a dihydro impurity and a metabolite of 8-Methoxypsoralen (M260795), also known as Methoxsalen. 9-METHOXY-2,3-DIHYDROFURO[3,2-G]COUMARIN has potential applications in the development of new drugs, particularly in the treatment of various medical conditions.
Used in Research and Development:
Due to its unique chemical structure and biological activities, 9-METHOXY-2,3-DIHYDROFURO[3,2-G]COUMARIN can be used as a research compound for studying the properties and potential applications of furocoumarin derivatives in various fields, including pharmaceuticals, agriculture, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 3779-03-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,7 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3779-03:
(6*3)+(5*7)+(4*7)+(3*9)+(2*0)+(1*3)=111
111 % 10 = 1
So 3779-03-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H10O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-3,6H,4-5H2,1H3
3779-03-1Relevant articles and documents
Synthetic models related to methoxalen and menthofuran-cytochrome P450 (CYP) 2A6 interactions. Benzofuran and coumarin derivatives as potent and selective inhibitors of CYP2A6
Yamaguchi, Yuki,Akimoto, Ichie,Motegi, Kyoko,Yoshimura, Teruki,Wada, Keiji,Nishizono, Naozumi,Oda, Kazuaki
, p. 997 - 1001 (2013/11/19)
Human microsomal cytochrome P450 (CYP) 2A6 contributes extensively to nicotine detoxication but also activates tobacco-specific procarcinogens to mutagenic products. We prepared a series of benzofuran and coumarin derivatives that have inhibitory effects on the activity of human CYP2A6. The reported compounds methoxalen and menthofuran had potent inhibitory effects on the activity of CYP2A6 with IC50 values of 0.47 μM and 1.27 μM, respectively. Synthetic benzofuran (4-methoxybenzofuran: IC50=2.20 μM) and coumarin (5-methoxycoumarin: IC50=0.13 μM and 6-methoxycoumarin: IC50=0.64 μM) derivatives, which have more selective effects than those of methoxalen and menthofuran, exhibited comparable activities against CYP2A6. These compounds can be used as a lead compounds in the design of CYP2A6 inhibitor drugs to reduce smoking and tobacco-related cancers.
Reduced and quaternized psoralens as photo-activated therapeutics
-
, (2008/06/13)
The invention features phototherapeutic compositions comprising Type 1, Type 2, or Type 3 psoralens and methods of using such compounds for treatment of proliferative diseases of skin, blood and bone marrow.
Transfer hydrogenations of furocoumarin derivatives
Heindel,Foster,Choudhuri
, p. 3817 - 3819 (2007/10/02)
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