68123-30-8 Usage
Description
2,3-DIHYDRO-9-HYDROXY-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE, also known as 4',5'-Dihydro-8-hydroxypsoralen, is a furancourmarin compound with inhibitory activity on CYP3A4 and prostaglandin E2 production. It is an impurity of 8-Methoxypsoralen (M260795), also known as Methoxsalen.
Uses
Used in Pharmaceutical Industry:
2,3-DIHYDRO-9-HYDROXY-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE is used as an impurity in the production of 8-Methoxypsoralen (M260795), also known as Methoxsalen, for its inhibitory activity on CYP3A4 and prostaglandin E2 production. This makes it a potential candidate for use in pharmaceutical applications where these inhibitory effects are desired.
Check Digit Verification of cas no
The CAS Registry Mumber 68123-30-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,1,2 and 3 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 68123-30:
(7*6)+(6*8)+(5*1)+(4*2)+(3*3)+(2*3)+(1*0)=118
118 % 10 = 8
So 68123-30-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H8O4/c12-8-2-1-6-5-7-3-4-14-10(7)9(13)11(6)15-8/h1-2,5,13H,3-4H2
68123-30-8Relevant articles and documents
Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 production
Ban, Hyun Seung,Lim, Soon Sung,Suzuki, Katsuya,Jung, Sang Hoon,Lee, Sanghyun,Lee, Yeon Sil,Shin, Kuk Hyun,Ohuchi, Kazuo
, p. 408 - 412 (2003)
We have isolated five furanocoumarins, byakangelicin, phellopterin, imperatorin, isoimperatorin, and oxypeucedanin methanolate, from the roots of Angelica dahurica (Umbelliferae) and prepared five semi-synthesized compounds by the partial reduction of eac
Reduced and quaternized psoralens as photo-activated therapeutics
-
, (2008/06/13)
The invention features phototherapeutic compositions comprising Type 1, Type 2, or Type 3 psoralens and methods of using such compounds for treatment of proliferative diseases of skin, blood and bone marrow.