3780-00-5

Basic information

• Product Name: (S)-1,1'-(1,2-propadiene-1,3-diyl)bisbenzene
• CAS NO: 3780-00-5
• Molecular Weight: 192.26
• Mol File: 3780-00-5.mol
• Article Data: 56

Chemical Properties

• CAS DataBase Reference: (S)-1,1'-(1,2-propadiene-1,3-diyl)bisbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1,1'-(1,2-propadiene-1,3-diyl)bisbenzene(3780-00-5)
• EPA Substance Registry System: (S)-1,1'-(1,2-propadiene-1,3-diyl)bisbenzene(3780-00-5)

Safety Data

• Hazardous Substances Data: 3780-00-5(Hazardous Substances Data)

Upstream product

• 4187-87-5 (R)-1-phenyl-2-propyn-1-ol 
• 1199-95-7 1-(trimethylstannyl)-2-phenylethyne 
• 100-52-7 benzaldehyde 
• 29127-97-7 2-Tosylazo-1,3-diphenylpropen 
• 100-42-5 styrene 
• 536-74-3 phenylacetylene 
• 1009080-91-4 C₂₀H₂₁NO 
• 1133970-54-3 (S)-1-((S)-1,3-diphenylprop-2-yn-1-yl)-2-(pyrrolidin-1-ylmethyl)-pyrrolidine 
• 51207-66-0 (S)-2-(1-pyrrolidinylmethyl)pyrrolidine 
• 946008-11-3 C₁₇H₁₄O₃ 
• 98-80-6 phenylboronic acid 
• 3234-51-3 1,1-dibromo-2-phenylcyclopropane 
• 2327-99-3 1-phenylpropadiene 
• 261759-73-3 carbonic acid 1,3-diphenylprop-2-ynyl ester methyl ester 

Downstream Products

• 3780-00-5 1-(3-phenyl-1,2-propadienyl)benzene 
• 17325-41-6 cis-1,2-Diphenyl-anti-3,4-dibenzylidenecyclobutane 
• 15408-55-6 4,4-Dichlor-1-phenyl-3-dichlormethylen-2-benzyliden-cyclobutan 
• 3780-00-5 (R)-1,3-diphenylallene 
• 41049-36-9 1-hydroxy-1,3-diphenylacetone 
• 51351-77-0 C₁₅H₁₂Ni(P(C₆H₅)3)2 
• 848245-36-3 (S,E)-[(Cp)2Zr(N(2,6-Me₂C₅H₃)C(CHC₆H₅)CHC₆H₅)] 

Relevant articles and documents

Copper-Catalyzed 1,1-Boroalkylation of Terminal Alkynes: Access to Alkenylboronates via a Three-Component Reaction

A copper-catalyzed three-component reaction of terminal alkynes, diazo compounds, and B2pin2 to prepare trisubstituted alkenylboronates has been developed. This difunctionalization of alkynes selectively occurs at the terminal carbon atom and proceeds via

Trifluoromethylation of Allenes: An Expedient Access to α-Trifluoromethylated Enones at Room Temperature

A silver(I) catalyzed regioselective trifluoromethylation of allenes using Langlois's salt (NaOSOCF3) is demonstrated. This transformation enables direct expedient access to α-trifluoromethylated acroleins, which are valuable synthons for a number of pharmaceuticals and agrochemicals containing vinyl-CF3 moieties. Versatility of this trifluoromethylation method has been established with good yield and excellent regioselectivity. Preliminary experiments and computational studies were carried out to elucidate the mechanistic insight of this protocol.

Matched Coupling of Propargylic Carbonates with Cyclopropanols

The ring opening-coupling reaction of cyclopropanols with propargylic carbonates affording synthetically attractive allenyl ketones has been developed. The mechanism involves the ligand-exchange reaction of in situ formed allenyl palladium methoxide with cyclopropanols followed by carbon-carbon bond cleavage and reductive elimination. The reactions proceeded smoothly under mild reaction conditions with Pd(0)/XPhos catalysis in the absence of any external base and displayed a wide scope and application to a steroidal skeleton. The efficiency of chirality transfer and synthetic utility of the allene products have also been demonstrated.