37856-26-1

Basic information

• Product Name: 3-(naphthalen-1-yl)-2-phenylquinazolin-4(3H)-one
• Synonyms: 3-(naphthalen-1-yl)-2-phenylquinazolin-4(3H)-one
• CAS NO: 37856-26-1
• Molecular Weight: 348.404
• Mol File: 37856-26-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(naphthalen-1-yl)-2-phenylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(naphthalen-1-yl)-2-phenylquinazolin-4(3H)-one(37856-26-1)
• EPA Substance Registry System: 3-(naphthalen-1-yl)-2-phenylquinazolin-4(3H)-one(37856-26-1)

Safety Data

• Hazardous Substances Data: 37856-26-1(Hazardous Substances Data)

Upstream product

• 3084-52-4 2-phenyl-4H-1,3-benzoxazin-4-one 
• 134-32-7 1-amino-naphthalene 
• 57115-11-4 2-amino-N-(naphthalen-1-yl)benzamide 
• 108-88-3 toluene 

Relevant articles and documents

Synthesis of 2-aryl quinazolinones: Via iron-catalyzed cross-dehydrogenative coupling (CDC) between N-H and C-H bonds

Herein, we describe the direct synthesis of quinazolinones via cross-dehydrogenative coupling between methyl arenes and anthranilamides. The C-H functionalization of the benzylic sp3 carbon is achieved by di-t-butyl peroxide under air, and the subsequent amination-aerobic oxidation process completes the annulation process. Iron catalyzed the whole reaction process and various kinds of functional groups were tolerated under the reaction conditions, providing 31 examples of 2-aryl quinazolinones using methyl arene derivatives in yields of 57-95percent. The synthetic potential has been demonstrated by the additional synthesis of aryl-containing heterocycles. This journal is