381212-20-0

Basic information

• Product Name: Phosphine oxide, tris(3,5-dimethylphenyl)-
• Synonyms: tris(3,5-dimethylphenyl)phosphine oxide;Phosphine oxide,tris(3,5-dimethylphenyl);(3,5-diMePh)3PO
• CAS NO: 381212-20-0
• Molecular Formula: C24H27OP
• Molecular Weight: 362.44400
• Mol File: 381212-20-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 559.5±50.0 °C(Predicted)
• Density: 1.09±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Phosphine oxide, tris(3,5-dimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, tris(3,5-dimethylphenyl)-(381212-20-0)
• EPA Substance Registry System: Phosphine oxide, tris(3,5-dimethylphenyl)-(381212-20-0)

Safety Data

• Hazardous Substances Data: 381212-20-0(Hazardous Substances Data)

Upstream product

• 556-96-7 5-bromo-1,3-xylene 
• 69227-47-0 tris(3,5-dimethylphenyl)phosphine 

Downstream Products

• 69227-47-0 tris(3,5-dimethylphenyl)phosphine 
• 540743-30-4 rac-4,4',6,6'-tetramethyl-2,2'-bis[bis(3,5-dimethylphenyl)phosphinoyl]biphenyl 
• 540743-31-5 rac-4,4',6,6'-tetramethyl-2,2'-bis[bis(3,5-dimethylphenyl)phosphino]biphenyl 

Relevant articles and documents

Electrophilic Phosphonium Cation-Mediated Phosphane Oxide Reduction Using Oxalyl Chloride and Hydrogen

The metal-free reduction of phosphane oxides with molecular hydrogen (H2) using oxalyl chloride as activating agent was achieved. Quantum-mechanical investigations support the heterolytic splitting of H2 by the in situ formed electrophilic phosphonium cation (EPC) and phosphane oxide and subsequent barrierless conversion to the phosphane and HCl. The reaction can also be catalyzed by the frustrated Lewis pair (FLP) consisting of B(2,6-F2C6H3)3 and 2,6-lutidine or phosphane oxide as Lewis base. This novel reduction was demonstrated for triaryl and diaryl phosphane oxides providing access to phosphanes in good to excellent yields (51–93 %).