38289-30-4

Basic information

• Product Name: trans-4-Hexylcyclohexanecarboxylic acid
• Synonyms: 4-TRANS-HEXYL CYCLOHEXANE CARBOXYLIC ACID;Trans-4-HexylcyclohexaneCarboxylicacid,6HaC13H24O2;trans-4-n-Hexylcyclohexanecarboxylicacid;trans-4-Hexyl Cyclohexane Carboxylic Acid;6HA
• CAS NO: 38289-30-4
• Molecular Formula: C₁₃H₂₄O₂
• Molecular Weight: 212.32846
• Mol File: 38289-30-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 321.2 °C at 760 mmHg
• Flash Point: 155.8 °C
• Appearance: /
• Density: 0.955 g/cm³
• Vapor Pressure: 6.27E-05mmHg at 25°C
• Refractive Index: 1.466
• Storage Temp.: 2-8°C
• PKA: 4.94±0.10(Predicted)
• CAS DataBase Reference: trans-4-Hexylcyclohexanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-Hexylcyclohexanecarboxylic acid(38289-30-4)
• EPA Substance Registry System: trans-4-Hexylcyclohexanecarboxylic acid(38289-30-4)

Safety Data

• Hazardous Substances Data: 38289-30-4(Hazardous Substances Data)

Usage

Uses

Intermediates of Liquid Crystals

InChI:InChI=1/C13H24O2/c1-2-3-4-5-6-11-7-9-12(10-8-11)13(14)15/h11-12H,2-10H2,1H3,(H,14,15)/t11-,12-

Upstream product

• 21643-38-9 4-hexylbenzoic acid 
• 38792-92-6 4-n-hexylcyclohexanecarboxylic acid 

Downstream Products

• 83867-06-5 thallium salt of 4-hexyl-trans-cyclohexanecarboxylic acid 
• 120406-80-6 trans-1-acryloyl-4-n-hexylcyclohexane 
• 94516-33-3 3-n-propyl-6-(trans-4-n-hexylcyclohexyl)-3,4-dihydro-2-N-piperidino-2H-pyrane 
• 94142-19-5 5-n-propyl-2-(trans-4-n-hexylcyclohexyl)pyridine 
• 94142-31-1 3-n-propyl-6-(cyclohexyl)-3,4-dihydro-2-N-piperidino-2H-pyrane 
• 94142-22-0 3-ethyl-6-(cyclohexyl)-3,4-dihydro-2-N-piperidino-2H-pyrane 
• 94142-17-3 C₁₄H₂₁N 
• 94142-16-2 5-ethyl-2-cyclohexylpyridine 
• 2177-34-6 1-cyclohexylprop-2-en-1-one 
• 71458-15-6 1-Bromomethyl-4-hexyl-cyclohexane 
• 125533-13-3 2-(4-Hexyl-cyclohexyl)-1-phenyl-ethanone 
• 125533-02-0 [2-(4-Hexyl-cyclohexyl)-ethyl]-benzene 
• 89587-94-0 (4-Hexyl-cyclohexyl)-acetic acid 

Relevant articles and documents

Improved synthesis of trans-4-alkylcyclohexane carboxylic acids

Several stereomerically pure amino acid derivatives containing the N-terminal trans-4-alkylcyclohexanoyl fragment were obtained. Hydrogenation of 4-alkylbenzoic acids in the presence of a special Ru-Ni/C catalytic system and isomerization of the resulting mixture of trans- and cis-isomers of 4-alkylcyclohexanecarboxylic acids were used as the key steps. The stereomeric configuration of all compounds was confirmed by 1H NMR spectroscopy. The compounds obtained possess a broad biological activity potential and are useful intermediates in the synthesis of stereomerically pure modified peptides.

ISOMERIZATION UNDER THE INFLUENCE OF p-TOLUENESULFONIC ACID.

The authors have investigated the influence of a mild acid isomerization catalyst, p-toluenesulfonic acid (TSA), on 4-butyl- (Ia) and 4-hexyl- (Ib) cyclohexanecarboxylic acids and their methyl esters (IIa, IIb). It is found that p-toluenesulfonic acid is an effective catalyst of cis-trans isomerization of 4-alkylcyclohexanecarboxylic acids and their esters; removal of water from the reaction medium raises the isomerization rate. Esters of alkylcyclohexanecarboxylic acids are isomerized at higher rates than the acids themselves. A probable mechanism of the acid-catalyzed isomerization reaction is proposed.

Long-acting contraceptive agents: Alphatic and alicyclic carboxylic esters of levonorgestrel

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