383421-27-0Relevant articles and documents
A porphyrin tetramer for a positive homotropic allosteric recognition system: Efficient binding information transduction through butadiynyl axis rotation
Kubo, Yohei,Ikeda, Masato,Sugasaki, Atsushi,Takeuchi, Masayuki,Shinkai, Seiji
, p. 7435 - 7438 (2001)
A porphyrin tetramer 1 was newly designed and synthesized to construct a novel allosteric guest-binding system. Compound 1 has a butadiynyl rotational axis, which is expected to act as a guest-binding information transducer. In chloroform, 1 can bind bidentate amines, such as 1,3-di(4-piperidyl)propane (DPP), in an allosteric manner to produce a 1:2 1/diamine complex with a Hill coefficient of 1.9.