3849-22-7

Basic information

• Product Name: [1(3H)-ISOINDOLINONE-3-YL]ACETIC ACID
• Synonyms: (3-OXO-2,3-DIHYDRO-1 H-ISOINDOL-1-YL)-ACETIC ACID;[1(3H)-ISOINDOLINONE-3-YL]ACETIC ACID;CHEMBRDG-BB 4140754;2-(3-ketoisoindolin-1-yl)acetic acid;2-(3-oxo-1,2-dihydroisoindol-1-yl)acetic acid;2-(3-oxo-1,2-dihydroisoindol-1-yl)ethanoic acid;(3-oxo-2,3-dihydro-1H-isoindol-1-yl)acetic acid(SALTDATA: FREE);2-(3-oxoisoindolin-1-yl)acetic acid
• CAS NO: 3849-22-7
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.18
• Mol File: 3849-22-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 506.5°Cat760mmHg
• Flash Point: 260.1°C
• Appearance: /
• Density: 1.334g/cm³
• Vapor Pressure: 4.42E-11mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: [1(3H)-ISOINDOLINONE-3-YL]ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: [1(3H)-ISOINDOLINONE-3-YL]ACETIC ACID(3849-22-7)
• EPA Substance Registry System: [1(3H)-ISOINDOLINONE-3-YL]ACETIC ACID(3849-22-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 3849-22-7(Hazardous Substances Data)

Usage

General Description

[1(3H)-ISOINDOLINONE-3-YL]ACETIC ACID is a chemical compound with a complex and specific molecular structure. It is classified as an isoindolinone derivative, which is a type of heterocyclic compound. The acetic acid group attached to the isoindolinone ring gives the molecule acidic properties. [1(3H)-ISOINDOLINONE-3-YL]ACETIC ACID is used in various chemical and biochemical applications, such as in the synthesis of pharmaceuticals, agrochemicals, and materials. Its unique structure and properties make it an important building block for the production of drugs and other organic compounds.

InChI:InChI=1/C10H9NO3/c12-9(13)5-8-6-3-1-2-4-7(6)10(14)11-8/h1-4,8H,5H2,(H,11,14)(H,12,13)

Upstream product

• 55-21-0 benzamide 
• 1354694-26-0 (E)-ethyl 3-(2-carbamoylphenyl)acrylate 
• 7468-67-9 o-formylbenzonitrile 
• 1345532-47-9 2-(3-oxo-2,3-dihydro-1H-isoindol-1-yl)malonic acid dimethyl ester 
• 135447-28-8 (3-oxo-isoindolin-1-ylidene)-malonic acid diethyl ester 
• 131-91-9 1-Nitroso-2-naphthol 
• 50620-99-0 alpha-cyanocinnamic acid ethyl ester 
• 27510-48-1 (Z)-3-(2-cyanophenyl)prop-2-enoic acid 
• 141-82-2 malonic acid 
• 119-67-5 o-carboxybenzaldehyde 
• 14120-21-9 (o-carbamoylbenzoyl)acetic acid 
• 61147-65-7 2-cyano-cinnamic acid 
• 4403-34-3 phthalimidine-Δ^3,α-acetic acid 
• 33779-03-2 2-(2-methoxycarbonylethyl)benzoic acid 

Downstream Products

• 103255-66-9 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)carbonylmethylisoindolin-1-one 
• 133737-32-3 2-(7-chloro-1,8-naphthyridine-2-yl)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinone 
• 1404559-32-5 3-{2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1H-isoindol-1-one 
• 261624-09-3 benzoatosubphthalocyaninatoboron 
• 935686-58-1 (2-Benzyl-3-oxo-2,3-dihydro-1H-isoindol-1-yl)-acetic acid benzyl ester 
• 52952-31-5 tetrabenzoporphyrin 
• 210688-56-5 PD 168568 
• 210688-55-4 1,3-dihydro-3-(2-tosylethyl)-2H-isoindol-1-one 

Relevant articles and documents

Ru(II)-Catalyzed Controlled Cross-Dehydrogenative Coupling of Benzamides with Activated Olefins via Weakly Coordinating Primary Amides

Ru(II)-catalyzed regioselective ortho-alkenylation of primary benzamides with activated olefins has been realized over the competitive cyclized products. This reaction overall proceeds via a cross-dehydrogenative coupling (CDC) reaction using a simple and

Synthesis and pharmacological evaluation of functionalized isoindolinones on GABA-activated chloride currents in rat cerebellum granule cells in culture

A focused N-substituted 3-(2-piperazin-1-yl-2-oxoethyl)-2-(pyridin-2-yl)iso-indolin-1-ones small library was synthesized for modulation of GABA-A receptor function and compared to Zopiclone for the ability to increase GABA-activated chloride currents. All

Cobalt-catalyzed one-pot three-component coupling route to β-acetamido carbonyl compounds: A general synthetic protocol for γ-lactams

An efficient improved procedure for the synthesis of β-acetamido carbonyl compounds is developed by a cobalt(II) chloride-catalyzed three-component coupling protocol. The procedure is also amenable to the synthesis of γ-lactams by a three-component coupli