38650-84-9

Basic information

• Product Name: Methyl 2,2-difluoropropanoate
• Synonyms: Methyl 2,2-difluoropropanoate;Propanoic acid, 2,2-difluoro-, Methyl ester;Methyl 2,2-difluoropropionate
• CAS NO: 38650-84-9
• Molecular Formula: C₄H₆F₂O₂
• Molecular Weight: 124.0860464
• Mol File: 38650-84-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 68.3±25.0 °C(Predicted)
• Appearance: /
• Density: 1.138±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Methyl 2,2-difluoropropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2,2-difluoropropanoate(38650-84-9)
• EPA Substance Registry System: Methyl 2,2-difluoropropanoate(38650-84-9)

Safety Data

• Hazardous Substances Data: 38650-84-9(Hazardous Substances Data)

Usage

General Description

Methyl 2,2-difluoropropanoate is a chemical compound with the molecular formula C5H8O2F2. It is a clear, colorless liquid that is flammable and has a fruity odor. This chemical is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. Methyl 2,2-difluoropropanoate is also used as a solvent in various industrial processes. It is important to handle this chemical with care as it can be hazardous if not used properly.

Upstream product

• 1319011-33-0 methyl 2,2-difluoro-3-iodopropanoate 
• 55991-65-6 [1-(4-methoxyphenyl)vinyloxy]trimethylsilane 

Downstream Products

• 33420-52-9 2,2-difluoropropan-1-ol 
• 51368-10-6 4,4-difluoro-3-oxo-pentanoic acid ethyl ester 
• 141-97-9 ethyl acetoacetate 

Relevant articles and documents

Α, α-difluoropropionic production of esters

PROBLEM TO BE SOLVED: To provide a practical method of producing α,α-difluoro esters important as pharmaceutical and agricultural chemical intermediates. SOLUTION: The α,α-difluoro esters are produced by reacting α-halogeno-α-fluoro esters with salts or complexes comprising an organic base and hydrogen fluoride. Dehydrohalogenation of side reaction is controlled in the production method. Only α-fluoro-α,β-unsaturated esters of by-products are treated to be brought specifically into a high boiling-point, a boiling point difference gets remarkably large thereby between the α,α-difluoro ester of an objective product and the unsaturated ester of by-product, and a high purity product of the objective product is efficiently obtained by fractional distillation of a simple operation. The method is the practical method of producing the α,α-difluoro esters capable of solving a problem point in a prior technique. COPYRIGHT: (C)2012,JPOandINPIT