38678-61-4

Basic information

• Product Name: H-PHE-GLY-NH2 HCL
• Synonyms: H-PHE-GLY-NH2 HCL;H-Phe-Gly-NH2
• CAS NO: 38678-61-4
• Molecular Formula: C₁₁H₁₅N₃O₂
• Molecular Weight: 221.26
• Mol File: 38678-61-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: H-PHE-GLY-NH2 HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-PHE-GLY-NH2 HCL(38678-61-4)
• EPA Substance Registry System: H-PHE-GLY-NH2 HCL(38678-61-4)

Safety Data

• Hazardous Substances Data: 38678-61-4(Hazardous Substances Data)

Usage

General Description

H-PHE-GLY-NH2 HCL is a chemical compound that consists of a dipeptide composed of phenylalanine (PHE) and glycine (GLY) linked together with an amide group (NH2) and a hydrochloride (HCL) salt form. Phenylalanine is an essential amino acid that plays a crucial role in protein synthesis and serves as a precursor for neurotransmitters such as dopamine, norepinephrine, and epinephrine. Glycine is a nonessential amino acid that is important for the synthesis of proteins and plays a role in the central nervous system as an inhibitory neurotransmitter. In its HCL form, the compound is a salt that can be more easily dissolved in water and has a slightly acidic pH. Overall, H-PHE-GLY-NH2 HCL is a compound with important biological functions and solubility properties.

Upstream product

• 35661-40-6 N-Fmoc L-Phe 
• 1349173-17-6 Fmoc-Phe-Gly-NH₂ 
• 63-91-2 L-phenylalanine 
• 598-41-4 H-Gly-NH₂ 
• 3674-06-4 Boc-Phe-ONSu 
• 42726-70-5 Boc-Phe-Gly-NH₂ 
• 17187-05-2 Z-L-phenylalanylglycinamide 

Downstream Products

• 1349173-14-3 C₁₅H₂₀N₄O₃ 
• 1349173-18-7 C₃₄H₃₄N₄O₃ 
• 1402723-37-8 C₂₄H₂₇N₅O₄ 
• 165900-95-8 Z-Tyr(SO₃H)-D-Ala-Phe-Gly-NH₂ 
• 165900-94-7 Z-Tyr-D-Ala-Phe-Gly-NH₂ 
• 118743-40-1 H-D-Ala-Phe-Gly-NH₂ 

Relevant articles and documents

Aziridine-mediated ligation and site-specific modification of unprotected peptides

A synthesis of aziridine-containing peptides via the Cu(II)-promoted coupling of unprotected peptide thioacids and N-H aziridine-2-carbonyl peptides is reported. The unique reactivity of the resulting N-acylated aziridine-2-carbonyl peptides facilitates t

2,2-Dimethyl-2-(o-nitrophenyl)acetyl (DMNA) as an assisted cleavage protecting group for amines

2,2-Dimethyl-2-(o-nitrophenyl)acetyl group (DMNA) was explored as an assisted cleavage protecting group for amines and a one-step deprotection condition was developed for its efficient removal using hydrogenation in the presence of Pd-C or PtO2 catalyst and 10% HOAc in MeOH. DMNA was found to be especially useful for the synthesis of gem-diamino compounds using Hofmann rearrangement.