388118-61-4

Basic information

• Product Name: Pyridine, 4-[4-[[2-(1-methylethyl)phenyl]thio]-3-(trifluoromethyl)phenyl]-, 1-oxide
• CAS NO: 388118-61-4
• Molecular Formula: C21H18F3NOS
• Molecular Weight: 389.441
• Mol File: 388118-61-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyridine, 4-[4-[[2-(1-methylethyl)phenyl]thio]-3-(trifluoromethyl)phenyl]-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 4-[4-[[2-(1-methylethyl)phenyl]thio]-3-(trifluoromethyl)phenyl]-, 1-oxide(388118-61-4)
• EPA Substance Registry System: Pyridine, 4-[4-[[2-(1-methylethyl)phenyl]thio]-3-(trifluoromethyl)phenyl]-, 1-oxide(388118-61-4)

Safety Data

• Hazardous Substances Data: 388118-61-4(Hazardous Substances Data)

Upstream product

• 388118-59-0 4-(4-fluoro-3-trifluoromethyl-phenyl)-pyridine 
• 1692-15-5 4-pyridylboronic acid 
• 393-37-3 5-bromo-2-fluorobenzotrifluoride 
• 6262-87-9 2-isopropylbenzenethiol 
• 388118-60-3 4-(4-fluoro-3-trifluoromethyl-phenyl)-pyridine-1-oxide 

Downstream Products

• 388118-62-5 2-chloro-4-[4-(2-isopropyl-phenylsulfanyl)-3-trifluoromethyl-phenyl]-pyridine 

Relevant articles and documents

Amino-substituted heterocycles as isosteres of trans-cinnamides: Design and synthesis of heterocyclic biaryl sulfides as potent antagonists of LFA-1/ICAM-1 binding

2-Amino-4-phenyl pyridine and, to a lesser extent, 4-amino-6-phenyl pyrimidine, were established as isosteres of trans-cinnamide moiety. Applying this isosterism to previously reported p-arylthio cinnamides resulted in the identification of 4-amino-6-(p-arylthio)phenyl-pyrimidines and 2-amino-4-(p-arylthio)phenyl-pyridines as potent antagonists of LFA-1/ICAM-1 binding.