3958-56-3

Basic information

• Product Name: alpha-iodo-m-nitrotoluene
• Synonyms: alpha-iodo-m-nitrotoluene;1-(Iodomethyl)-3-nitrobenzene;1-Nitro-3-(iodomethyl)benzene;Einecs 223-556-8
• CAS NO: 3958-56-3
• Molecular Formula: C₇H₆INO₂
• Molecular Weight: 263.03251
• EINECS: 223-556-8
• Mol File: 3958-56-3.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 324.3 °C at 760 mmHg
• Flash Point: 149.9 °C
• Appearance: /
• Density: 1.928 g/cm³
• CAS DataBase Reference: alpha-iodo-m-nitrotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-iodo-m-nitrotoluene(3958-56-3)
• EPA Substance Registry System: alpha-iodo-m-nitrotoluene(3958-56-3)

Safety Data

• Hazardous Substances Data: 3958-56-3(Hazardous Substances Data)

Usage

General Description

Alpha-iodo-m-nitrotoluene is a chemical compound that is a derivative of toluene, which is commonly used as a solvent and as a precursor in the production of dyes and pharmaceuticals. The "alpha" in its name indicates the position of the iodine atom on the benzene ring, and the "m" refers to the relative positioning of the nitro and methyl groups. alpha-iodo-m-nitrotoluene is a pale yellow crystalline solid and is primarily used as an intermediate in the synthesis of other organic compounds. It can also be used as a reagent in various chemical reactions, such as halogenation and nitration. However, alpha-iodo-m-nitrotoluene is a hazardous substance that can cause skin and eye irritation and should be handled with appropriate safety precautions.

Upstream product

• 619-25-0 3-Nitrobenzyl alcohol 
• 619-23-8 3-Nitrobenzyl chloride 
• 1877-73-2 3-nitro-benzeneacetic acid 
• 142509-31-7 1-((methoxymethoxy)methyl)-3-nitrobenzene 
• 1058649-37-8 3-nitro-1-[(ethoxymethoxy)methyl]benzene 
• 99-61-6 3-nitro-benzaldehyde 
• 3958-57-4 1-bromomethyl-3-nitrobenzene 

Downstream Products

• 1379600-72-2 bis(3-nitrobenzyl)(3-aminobenzyl)amine 
• 1379600-73-3 bis(3-nitrobenzyl){3-[N'-(4-butylphenyl)ureido]benzyl}amine 
• 1379600-74-4 bis(3-aminobenzyl){3-[N'-(4-butylphenyl)ureido]benzyl}amine 
• 1379600-68-6 bis{3-[N'-(4-trifluoromethylphenyl)ureido]benzyl}{3-[N'-(4-butylphenyl)ureido]benzyl}amine 
• 1379600-69-7 bis{3-[N'-(4-methoxyphenyl)ureido]benzyl}{3-[N'-(4-butylphenyl)ureido]-benzyl}amine 
• 1379600-70-0 bis{3-[N'-(benzyl)ureido]benzyl}{3-[N'-(4-butylphenyl)ureido]benzyl}amine 
• 1379600-71-1 bis(3-nitrobenzyl)(3-azidobenzyl)amine 
• 786696-32-0 C₁₇H₁₄N₂O₁₁S₃ 
• 136794-82-6 4'-O-demethyl-4β-[(3''-aminobenzyl)amino]-4-desoxypodophyllotoxin 
• 15539-78-3 (3-nitrophenyl)methyl nitrate 
• 136794-72-4 4'-O-demethyl-4β-[(3''-nitrobenzyl)amino]-4-desoxypodophyllotoxin 
• 34063-52-0 1-Nitro-3-nitromethyl-benzene 

Relevant articles and documents

A mild and highly chemoselective iodination of alcohol using polymer supported DMAP

The synthesis of organic compounds using polymer supported catalysts and reagents, where the required product is always in solution, has been of great interest in recent years, both in industries and academia especially in pharmaceutical research. Here, a simple and efficient method for conversion of alcohols into their iodides in high yield using polymer supported 4-(Dimethylamino)pyridine (DMAP) is described. Polymer supported DMAP is used in catalytic amount and is recovered and reused several times. Additionally, this method is highly chemoselective. [Figure not available: see fulltext.]

Scalable, easy synthesis, and efficient isolation of arylnitromethanes: a revival of the Victor Meyer reaction

A modified approach to synthesize and isolate arylnitromethanes is described. The method takes advantage of the significant difference in acidity between the arylnitromethane and the major impurity of the reaction, the nitrite ester. The arylnitromethanes resulting from this process are obtained in high yields and are analytically pure, i.e., they do not require distillation or further purification, which is a comfortable improvement of the ancestral Victor Meyer reaction.

PROCESS FOR THE PREPARATION OF N-IODOAMIDES

The present invention provides new stable crystalline N-iodoamides - 1-iodo- 3,5,5-trimethylhydantoin (1-ITMH) and 3-iodo-4,4-dimethyl-2-oxazolidinone (IDMO). The present invention further provides a process for the preparation of organic iodides using N-iodoamides of this invention and recovery of the amide co-products from waste water.