39794-75-7 Usage
Description
Ethyl (p-tosyloxy)acetate, also known as (Toluene-4-sulfonyloxy)-acetic acid ethyl ester, is a colorless solid that serves as an important intermediate in the synthesis of various pharmaceutical compounds. Its chemical structure, characterized by the presence of a tosyloxy group and an ester functional group, makes it a versatile building block in organic chemistry and drug development.
Uses
Used in Pharmaceutical Industry:
Ethyl (p-tosyloxy)acetate is used as a key intermediate in the synthesis of Tosylglycolic Acid (T664020), which is an essential precursor for the production of Cefmetazole (C242850). Cefmetazole is a semi-synthetic antibiotic belonging to the cephalosporin class, widely used for treating various bacterial infections.
Ethyl (p-tosyloxy)acetate is used as a synthetic intermediate for [the development of pharmaceutical compounds] because of its unique chemical structure and reactivity, which allows for the creation of a wide range of therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, Ethyl (p-tosyloxy)acetate is used as a versatile building block for [the synthesis of various organic compounds] due to its ability to undergo a range of chemical reactions, such as nucleophilic substitutions, eliminations, and rearrangements. This makes it a valuable tool for the development of new molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 39794-75-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,7,9 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 39794-75:
(7*3)+(6*9)+(5*7)+(4*9)+(3*4)+(2*7)+(1*5)=177
177 % 10 = 7
So 39794-75-7 is a valid CAS Registry Number.
39794-75-7Relevant articles and documents
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Newman,Magerlein
, p. 469 (1947)
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Synthesis of thioether andrographolide derivatives and their inhibitory effect against cancer cells
Liu, Yi,Liang, Ren-Ming,Ma, Qing-Ping,Xu, Kai,Liang, Xin-Yong,Huang, Wei,Sutton, Robert,Ding, Jie,O'Neil, Paul M.,Cheng, Chun-Ru
supporting information, p. 1268 - 1274 (2017/07/07)
A series of novel thioether andrographolide derivatives were synthesized by incorporating various aromatic (or heteroaromatic) substituents into C-12 or 14-OH. A total of 38 andrographolide derivatives were prepared and evaluated for their in vitro inhibi
Synthesis of [11C]PBR06 and [18F]PBR06 as agents for positron emission tomographic (PET) imaging of the translocator protein (TSPO)
Wang, Min,Gao, Mingzhang,Miller, Kathy D.,Zheng, Qi-Huang
experimental part, p. 1331 - 1340 (2011/11/06)
The translocator protein 18 kDa (TSPO) is an attractive target for molecular imaging of neuroinflammation and tumor progression. [ 18F]PBR06, a fluorine-18 labeled form of PBR06, is a promising PET TSPO radioligand originally developed at NIMH.
