40128-87-8

Basic information

• Product Name: 11α-hydroxy-3,17β-dibenzyloxyoestra-1,3,5(10)-triene
• Synonyms: 11α-hydroxy-3,17β-dibenzyloxyoestra-1,3,5(10)-triene
• CAS NO: 40128-87-8
• Molecular Weight: 468.636
• Mol File: 40128-87-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 11α-hydroxy-3,17β-dibenzyloxyoestra-1,3,5(10)-triene(CAS DataBase Reference)
• NIST Chemistry Reference: 11α-hydroxy-3,17β-dibenzyloxyoestra-1,3,5(10)-triene(40128-87-8)
• EPA Substance Registry System: 11α-hydroxy-3,17β-dibenzyloxyoestra-1,3,5(10)-triene(40128-87-8)

Safety Data

• Hazardous Substances Data: 40128-87-8(Hazardous Substances Data)

Upstream product

• 40128-86-7 3,17β-Bis(benzyloxy)estra-1,3,5(10),9(11)-tetraene 
• 100-39-0 benzyl bromide 
• 53-16-7 Estrone 
• 791-69-5 9⁽¹¹⁾-Dehydroestradiol 
• 1089-80-1 3-hydroxy-estra-1,3,5⁽¹⁰⁾,9⁽¹¹⁾-tetraen-17-one 
• 69455-04-5 3,17β-bis(benzyloxy)estra-1,3,5(10)-triene 
• 50-28-2 estradiol 

Downstream Products

• 756844-03-8 11β-benzylthioestra-1,3,5(10)-triene-3,17β-diol 
• 756844-01-6 3,17β-bis(benzyloxy)-11β-methylthioestra-1,3,5(10)-triene 
• 756843-99-9 3,17β-bis(benzyloxy)-11β-benzylthioestra-1,3,5(10)-triene 
• 89155-71-5 (8S,9S,13S,14S,17S)-3,17-bis(benzyloxy)-13-methyl-6,7,8,9,12,13,14,15,16,17-decahydro-11H-cyclopenta[a]phenanthren-11-one 
• 5444-22-4 11beta-Hydroxyestradiol 
• 61665-15-4 17α-ethinyl-11α-methoxy 1,3,5(10)-estratriene-3,17β-diol 
• 166183-96-6 3,17β-Bis(benzyloxy)-11α-phenylestra-1,3,5(10)-trien-11β-ol 
• 166183-98-8 3,17β-Bis(benzyloxy)-11β-phenylestra-1,3,5(10)-triene 
• 166183-95-5 3,17β-Bis(benzyloxy)-11α-ethenylestra-1,3,5(10)-trien-11β-ol 
• 166183-97-7 3,17β-Bis(benzyloxy)-11β-ethynylestra-1,3,5(10)-triene 
• 64109-72-4 11beta-ethyl-estradiol 
• 129000-34-6 11β-(1-ethenyl)estra-1,3,5(10)-triene-3,17β-diol 3,17-bis(benzyl ether) 
• 534572-56-0 3,17β-dibenzyloxy(11β-toluenesulfonyloxymethyl)estra-1,3,5(10)-triene 
• 342898-65-1 11α-allyl-3,17β-dibenzyloxyestra-1,3,5(10)-triene-11β-ol 

Relevant articles and documents

Compound for targeted ubiquitination degradation of ERalpha protein and application thereof

The invention provides a compound with estrogen receptor alpha (ERalpha) activity, and particularly provides a 1,3,5-triazine compound with a general formula (I) or a general formula (II) or a pharmaceutically acceptable salt thereof. The definitions of the groups are as described in the specification. The compound disclosed by the invention has ERalpha degradation activity and can be used for preparing medicines for treating human breast cancer and endometrial cancer.

Synthesis and evaluation of B-, C-, and D-ring-substituted estradiol carboxylic acid esters as locally active estrogens

We have synthesized derivatives of estradiol that are structurally modified to serve as "soft" estrogens and act within a geographically limited area of the body; estrogens without systemic action. We have previously shown with 16α-substituted analogues o

11α-Methoxy estradiol and estriol derivatives. Antiestrogen activity of 11α-methoxy-17 α-ethynylestradiol: RU 16 117

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