402-05-1 Usage
Description
2-Bromo-5-trifluoromethylphenol is an organic compound characterized by the presence of a bromine atom at the 2nd position and a trifluoromethyl group at the 5th position on a phenol molecule. It exhibits the chemical properties of a light brown liquid.
Uses
Used in Pharmaceutical Industry:
2-Bromo-5-trifluoromethylphenol is used as a reactant for the synthesis of benzimidazolone and benzothiazolone compounds, which serve as AMPA receptor modulators. These modulators are crucial in the development of drugs targeting neurological disorders and conditions related to the central nervous system.
2-Bromo-5-trifluoromethylphenol's unique structure and reactivity make it a valuable intermediate in the synthesis of various pharmaceutical compounds, contributing to the advancement of drug discovery and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 402-05-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 402-05:
(5*4)+(4*0)+(3*2)+(2*0)+(1*5)=31
31 % 10 = 1
So 402-05-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4BrF3O/c8-5-2-1-4(3-6(5)12)7(9,10)11/h1-3,12H
402-05-1Relevant articles and documents
DERIVATIVES OF 6-SUBSTITUTED TRIAZOLOPYRIDAZINES AS REV-ERB AGONISTS
-
Page/Page column 52-53; 89, (2013/04/13)
The present invention provides novel 6-substituted [1,2,4]triazolo[4,3-b]pyridazines that are agonists of Rev-Erb. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the activation of Rev-Erb has therapeutic effects, for instance in inflammatory and circadian rhythm-related disorders or cardiometabolic diseases.
