402741-11-1

Basic information

• Product Name: 3-Oxazolidinecarboxylic acid, 5-(acetyloxy)-2-oxo-4-phenyl-, 1,1-dimethylethyl ester, (4R,5S)-
• CAS NO: 402741-11-1
• Molecular Formula: C16H19NO6
• Molecular Weight: 321.33
• Mol File: 402741-11-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Oxazolidinecarboxylic acid, 5-(acetyloxy)-2-oxo-4-phenyl-, 1,1-dimethylethyl ester, (4R,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxazolidinecarboxylic acid, 5-(acetyloxy)-2-oxo-4-phenyl-, 1,1-dimethylethyl ester, (4R,5S)-(402741-11-1)
• EPA Substance Registry System: 3-Oxazolidinecarboxylic acid, 5-(acetyloxy)-2-oxo-4-phenyl-, 1,1-dimethylethyl ester, (4R,5S)-(402741-11-1)

Safety Data

• Hazardous Substances Data: 402741-11-1(Hazardous Substances Data)

Upstream product

• 402741-08-6 (4R,5S)-5-acetyl-3-(4-methoxyphenyl)-4-phenyloxazolidin-2-one 
• 100-52-7 benzaldehyde 
• 24424-99-5 di-tert-butyl dicarbonate 
• 402741-09-7 (4R,5S)-5-acetyl-2-oxo-4-phenyloxazolidine-3-carboxylic acid tert-butyl ester 
• 402741-05-3 (1R,2S)-2-hydroxy-1-(4-methoxyphenylamino)-1-phenylbutan-3-one 

Downstream Products

• 117049-14-6 tert-butyl N-[(1S)-2-hydroxy-1-phenylethyl]carbamate 
• 67341-01-9 (R)-N-(tert-butoxycarbonyl)phenylglycinol 

Relevant articles and documents

The proline-catalyzed direct asymmetric three-component Mannich reaction: Scope, optimization, and application to the highly enantioselective synthesis of 1,2-amino alcohols

We have developed proline-catalyzed direct asymmetric three-component Mannich reactions of ketones, aldehydes, and amines. Several of the studied reactions provide β-amino carbonyl compounds (Mannich products) in excellent enantio-, diastereo-, regio-, an