4064-87-3

Basic information

• Product Name: 2,2-DIMETHYL-5-NITRO-1,3-DIOXANE
• Synonyms: 2,2-DIMETHYL-5-NITRO-1,3-DIOXANE
• CAS NO: 4064-87-3
• Molecular Formula: C₆H₁₁NO₄
• Molecular Weight: 161.16
• Mol File: 4064-87-3.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-DIMETHYL-5-NITRO-1,3-DIOXANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIMETHYL-5-NITRO-1,3-DIOXANE(4064-87-3)
• EPA Substance Registry System: 2,2-DIMETHYL-5-NITRO-1,3-DIOXANE(4064-87-3)

Safety Data

• Hazardous Substances Data: 4064-87-3(Hazardous Substances Data)

Usage

General Description

2,2-DIMETHYL-5-NITRO-1,3-DIOXANE is a chemical compound with the molecular formula C6H11NO5. It is a yellow crystalline solid that is primarily used as a reagent in organic synthesis and as a raw material in the production of pharmaceuticals and agrochemicals. 2,2-DIMETHYL-5-NITRO-1,3-DIOXANE is also known for its explosive properties and is considered to be potentially hazardous if not handled and stored properly. It is important to handle this chemical with caution and to adhere to safety guidelines when working with it.

Upstream product

• 60766-57-6 2,2-dimethyl-5-bromo-5-nitro-1,3-dioxane 
• 100-52-7 benzaldehyde 
• 4728-14-7 2,2-dimethyl-5-hydroxymethyl-5-nitro-1,3-dioxane 
• 1794-90-7 2-nitropropane-1,3-diol 
• 67-64-1 acetone 

Downstream Products

• 104143-48-8 2,2-dimethyl 5-nitro 5-p-nitrobenzyl 1,3-dioxane 
• 104440-15-5 2,2-dimethyl-5-nitro-5-phenylazo-[1,3]dioxane 
• 106377-87-1 2,2-dimethyl-5-nitro-5-p-tolylazo-[1,3]dioxane 
• 104622-21-1 5-(4-chloro-phenylazo)-2,2-dimethyl-5-nitro-[1,3]dioxane 
• 104912-19-8 2,2-dimethyl-5-nitro-5-(4-nitro-phenylazo)-[1,3]dioxane 
• 107821-92-1 2,2-dimethyl-5-nitro-5-[4-(4-nitro-phenylsulfanyl)-phenylazo]-[1,3]dioxane 
• 5086-75-9 2,2-dimethyl-5,5-dinitro-1,3-dioxane 
• 40137-24-4 5-amino-2,2-di-methyl-1,3-dioxane 
• 1023648-25-0 5-(2-{4-[3-(benzyloxy)phenylthio]-2-chlorophenyl}ethyl)-2,2-dimethyl-5-nitro[1,3]dioxane 
• 139157-69-0 1-methyl 2-(2,2-dimethyl 1,3-dioxane 5-ylidenemethyl) 5-nitroimidazole 
• 104143-49-9 2,2-dimethyl 5-p-nitrobenzylidene 1,3-dioxane 
• 1026324-26-4 3-(2,2-Dimethyl-[1,3]dioxan-5-ylcarbamoyl)-indazole-1-carboxylic acid benzyl ester 
• 186795-60-8 4-acetylamino-5-chloro-N-(2,2-dimethyl-1,3-dioxan-5-yl)-2-methoxybenzamide 

Relevant articles and documents

Synthesis of a new water soluble 2,2-bifunctionalized spin label and its application to troponin C

A new water soluble 2,2-bifunctionalized spin label (2,2E-BSL) having pyrrolidine nitroxide moiety was synthesized starting from a nitro compound with two hydroxymethyl group converted to the linkers of the 2,2E-BSL, and was applied to label troponin C (TnC). Labeled TnC through two linkages were successfully isolated, and 2,2E-BSL was proved to be immobilized on TnC by EPR measurement. Copyright

A PROCESS FOR MAKING 2-NITRO-1-ETHANOL DERIVATIVES

A process for making a 2-nitro-1-ethanol derivative of formula III: wherein R3 is as described herein is provided. Novel 2-nitro-1-ethanol derivatives provided.

An efficient total synthesis of a sphingosine-1-phosphate receptor agonist KRP-203

An efficient total synthesis of the S1P1 agonist, KRP-203, is described. The key step involves the conjugate addition of diethyl acetamidomalonate to a styrene compound to give the core structure of KRP-203. Multigram quantities of the targeted KRP-203, sufficient for several biological studies, were obtained in six steps with an overall yield of 58%.