40705-19-9

Basic information

• Product Name: 4-benzyloxy-6-bromo-3-hydroxybenzaldehyde
• Synonyms: 4-benzyloxy-6-bromo-3-hydroxybenzaldehyde
• CAS NO: 40705-19-9
• Molecular Weight: 307.144
• Mol File: 40705-19-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-benzyloxy-6-bromo-3-hydroxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyloxy-6-bromo-3-hydroxybenzaldehyde(40705-19-9)
• EPA Substance Registry System: 4-benzyloxy-6-bromo-3-hydroxybenzaldehyde(40705-19-9)

Safety Data

• Hazardous Substances Data: 40705-19-9(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 139-02-6 sodium phenoxide 
• 20194-18-7 sodium phenyl-methanolate 
• 67-56-1 methanol 
• 130400-91-8 4-benzyloxy-6-bromo-3-hydroxybenzyl alcohol 

Downstream Products

• 40705-22-4 4-benzyloxy-6-bromo-3-methoxybenzaldehyde 

Relevant articles and documents

Design of a Functional Chromene-Type Kobayashi Precursor: Gram-Scale Total Synthesis of Natural Xanthones by Highly Regioselective Aryne Annulation

The 2,2-dimethyl-2H-chromene motif is widely found in many bioactive molecules, and is a privileged structure in the pharmaceutical arena. We have developed a concise and regioselective approach to chromenes and chromanes through an aryne-based synthetic

REGIOSELECTIVE CLEAVAGE REACTION OF THE METHYLENEDIOXY RING IN AROMATIC COMPOUNDS CONTAINING ELECTRONWITHDRAWING GROUPS WITH SODIUM ALKOXIDES-ALCOHOLS IN DIMETHYL SULFOXIDE

The reaction of 6-bromopiperonal (1) with sodium alkoxides (MeONa or PhCH2ONa)-alcohols (MeOH or PhCH2OH), and sodium alkoxides (MeONa, PhCH2ONa or PhONa)-phenol (PhOH) in dimethyl sulfoxide gave 3-hydroxybenzene derivatives (3, 5 and 6) and 4-hydroxybenzene derivative (4), respectively.The reactivity and formational mechanism of various nucleophilic reagents (alkoxide anions) formed from the alcohols and phenol by sodium alkoxides in the regioselective cleavage reactions are discussed.