15930-53-7

Basic information

• Product Name: 2-Bromo-4,5-methylenedioxybenzaldehyde
• Synonyms: 6-BROMOPIPERONAL;6-BROMO-BENZO[1,3]DIOXOLE-4-CARBALDEHYDE;6-BROMO-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE;6-BROMO-1,3-BENZODIOXOLE-5-CARBOXALDEHYDE;6-BROMO-1,3-BENZODIOXOLE-5-CARBALDEHYDE;6-BROMO-3,4-METHYLENEDIOXYBENZALDEHYDE;BROMOPIPERONAL;TIMTEC-BB SBB001594
• CAS NO: 15930-53-7
• Molecular Formula: C₈H₅BrO₃
• Molecular Weight: 229.03
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Aldehydes;Building Blocks;C8;Carbonyl Compounds;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;O-Containing;Organic Building Blocks;Others
• Mol File: 15930-53-7.mol
• Article Data: 51

Chemical Properties

• Melting Point: 128-132 °C(lit.)
• Boiling Point: 309.2°Cat760mmHg
• Flash Point: 140.8°C
• Appearance: White to light yellow/Powder
• Density: 1.782
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.4730 (estimate)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Soluble in DMSO, methanol
• Sensitive: Air Sensitive
• CAS DataBase Reference: 2-Bromo-4,5-methylenedioxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4,5-methylenedioxybenzaldehyde(15930-53-7)
• EPA Substance Registry System: 2-Bromo-4,5-methylenedioxybenzaldehyde(15930-53-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• WGK Germany: 3
• RTECS: TO1576250
• HazardClass: IRRITANT
• Hazardous Substances Data: 15930-53-7(Hazardous Substances Data)

Usage

Description

2-Bromo-4,5-methylenedioxybenzaldehyde is an organic compound characterized by its white to light yellow powder form. It is a derivative of benzaldehyde, featuring a bromine atom at the 2nd position and two methoxy groups at the 4th and 5th positions on the benzene ring.

Uses

Used in Pharmaceutical Industry:
2-Bromo-4,5-methylenedioxybenzaldehyde is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the development of new drugs targeting specific receptors or enzymes.
Used in Chemical Synthesis:
In the field of organic chemistry, 2-Bromo-4,5-methylenedioxybenzaldehyde serves as a valuable building block for the creation of more complex molecules. Its reactive sites, including the aldehyde group and the bromine atom, can be further functionalized to produce a wide range of chemical products.
Used in Research and Development:
Due to its unique structure and reactivity, 2-Bromo-4,5-methylenedioxybenzaldehyde is also utilized in research and development for the study of chemical reactions, mechanisms, and the development of new synthetic methods.

InChI:InChI=1/C8H5BrO3/c9-6-1-5(3-10)8-7(2-6)11-4-12-8/h1-3H,4H2

Upstream product

• 120-57-0 piperonal 
• 75-15-0 carbon disulfide 
• 7726-95-6 bromine 
• 7553-56-2 iodine 
• 495-76-1 piperonol 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 64603-67-4 5-bromo-6-(chloromethyl)benzo[d][1,3]dioxole 
• 20850-43-5 5-(chloromethyl)-1,3-benzodioxole 
• 274-09-9 Methylenedioxybenzene 
• 6642-34-8 6-bromopiperonyl alcohol 
• 64-19-7 acetic acid 
• 74-97-5 chlorobromomethane 
• 4815-99-0 2-bromo-4,5-dihydroxybenzoaldehyde 
• 136-72-1 piperic acid 

Downstream Products

• 131814-93-2 2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether 
• 2973-59-3 2-bromoisovanillin 
• 40705-19-9 4-benzyloxy-6-bromo-3-hydroxybenzaldehyde 
• 120-57-0 piperonal 
• 60229-65-4 4,5:4',5'-bis(methylenedioxy)-1,1'-biphenyl-2,2'-dicarboxaldehyde 
• 84736-37-8 bis<(butanolidyl-4)-3 methyl>-6,6' hexamethoxy-2,3,4,2',3',4' biphenyle 
• 71209-04-6 <(butanolidyl-4)-3 methyl>-6 formyl-2' methylenedioxy-4',5' trimethoxy-2,3,4 biphenyle 
• 60546-62-5 6-bromopiperonylic acid 
• 145102-00-7 2-bromo-4-(propylthio)-5-hydroxybenzaldehyde 
• 6642-34-8 6-bromopiperonyl alcohol 
• 130400-90-7 C₈H₄⁽²⁾H₃BrO₃ 
• 62869-57-2 5,6-(methylenedioxy)phthalaldehydic acid 
• 854237-02-8 methyl 3-(1-formyl-3,4-methylenedioxy)benzoate 
• 2132-80-1 4,4'-Dimethoxybiphenyl 

Relevant articles and documents

Synthesis and Biological Evaluation of Benzo[d][1,3]Dioxol-5-yl Chalcones as Antiproliferating Agents

A series of chalcone derivatives were designed, synthesized, and evaluated for their cytotoxic potential. These molecules have showed promising cytotoxic activity with IC50 values ranging from 5.24 to 63.12 μm. Among them, conjugates 16k, 16m a

DNA binding ligands with in vivo efficacy in murine models of bacterial infection: Optimization of internal aromatic amino acids

DNA binding ligands with potent antimicrobial activity against Gram-positive bacteria were further optimized by variation of the internal aromatic amino acids. This modification led to compounds with improved in vivo efficacy in lethal murine models of peritonitis (methicillin-resistant S. aureus, MRSA) and lung infection (S. pneumoniae).

Total synthesis of enantiopure (+)-γ-lycorane using highly efficient Pd-catalyzed asymmetric allylic alkylation

A highly efficient short total synthesis of (+)-γ-lycorane (>99% ee, 41% overall yield) was achieved by using the asymmetric allylic alkylation in the key step catalyzed by palladium complexes with novel chiral biphenol-based monodentate phosphoramidite l

DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS

The present invention relates to dihydrocyclopenta-isoquinoline-sulfonamide derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular disorders caused by the interaction of IgE with the FcεRI receptor.

COMPOUNDS FOR THE INHIBITION OF UNREGULATED CELL GROWTH

The present invention discloses compounds for inhibition of uncontrolled cell proliferation particularly cancer stem cells. Particularly, the invention relates to compounds of Formula I to XXII for the treatment of cancer.