41215-40-1

Basic information

• Product Name: N-cyclopentylformamide
• CAS NO: 41215-40-1
• Molecular Formula: C₆H₁₁NO
• Molecular Weight: 113.1576
• Mol File: 41215-40-1.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 251°C at 760 mmHg
• Flash Point: 136.6°C
• Density: 0.98g/cm³
• Vapor Pressure: 0.0209mmHg at 25°C
• Refractive Index: 1.465
• CAS DataBase Reference: N-cyclopentylformamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclopentylformamide(41215-40-1)
• EPA Substance Registry System: N-cyclopentylformamide(41215-40-1)

Safety Data

• Hazardous Substances Data: 41215-40-1(Hazardous Substances Data)

Upstream product

• 96-41-3 Cyclopentanol 
• 151-50-8 potassium cyanide 
• 64-18-6 formic acid 
• 1003-03-8 Cyclopentamine 
• 50-00-0 formaldehyd 
• 124-38-9 carbon dioxide 
• 201230-82-2 carbon monoxide 
• 67-56-1 methanol 
• 287-92-3 Cyclopentane 
• 624-84-0 formic acid hydrazide 
• 1037739-35-7 (+/-)-2-(2-fluorophenyl)-2-methyloxirane 
• 68-12-2 N,N-dimethyl-formamide 
• 109-94-4 formic acid ethyl ester 
• 77287-34-4 formamide 

Downstream Products

• 68498-54-4 isocyanocyclopentane 
• 15205-23-9 N-cyclopentylbenzylamine 
• 40649-24-9 N-n-butylcyclopentylamine 
• 152945-45-4 Cyano-acetic acid 2-(4-chloro-phenyl)-1-cyclopentylcarbamoyl-2-oxo-ethyl ester 
• 75098-42-9 N,N-cyclopentylmethyl amine hydrochloride 
• 71475-27-9 N-benzyl-N-cyclopentylformamide 
• 1003-03-8 Cyclopentamine 

Relevant articles and documents

Amine formylation with CO2 and H2 catalyzed by heterogeneous Pd/PAL catalyst

For the first time, Pd supported on natural palygorskite was developed for amine formylation with CO2 and H2. Both secondary and primary amines with diverse structures could be converted into the desired formamides at 100 °C, and good to excellent yields were obtained.

N-doped carbon supported Pd catalysts for N-formylation of amines with CO2/H2

Using mesoporous N-doped carbons (NCs) derived from glucose and melamine as the supports, a series of Pd/NC catalysts were prepared, in which Pd nanoparticles with average size2 and H2 in ethanol without any additives. Especially, the catalyst Pd/NC-800-6.9% containing quaternary N showed the best performance, affording a series of formylamides in good or even excellent yields. Further investigation reveals that the interaction between the Pd nanoparticles and quaternary nitrogen in the NC support was responsible for the good performance of the catalyst.

Rapid synthesis method of biomass-based amide

The invention discloses a rapid synthesis method of biomass-based amide, which comprises the steps: formamide is used as an amine source, formic acid is used as a hydrogen source, biomass aldehyde andketone is used as a raw material, the direct addition of formamide and aldehyde and ketone components and the reduction of formic acid is promoted to prepare the corresponding formamide derivative byrapidly heating under microwave-assisted heating and in the absence of a solvent and a catalyst; the formamide derivative is selectively converted to the corresponding primary amide by alcoholysis under the action of a base. The microwave assisted heating reaction system of the invention has higher catalytic efficiency than the corresponding oil bath system, greatly shortens the reaction time, remarkably improves the selectivity. The conversion rate of the biomass aldehyde or ketone compound is at least 99%, and the yield of the formamide derivative can reach 85 to 99%; the formamide can be synthesized by alcoholysis to obtain a primary amide with a yield of 92 to 99%.