41530-32-9 Usage
Description
2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96, also known as Dimethyl 3-Methoxyallylidenemalonate, is a clear yellowish-green low melting solid with significant applications in the pharmaceutical industry. It is primarily used in the synthesis of pyridinonyl PDK1 inhibitors and pyrrolo[3,2-c]pyridine derivatives, which are essential as kinase inhibitors for cancer treatment.
Uses
Used in Pharmaceutical Industry:
2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96 is used as a key intermediate compound for the synthesis of pyridinonyl PDK1 inhibitors and pyrrolo[3,2-c]pyridine derivatives. These compounds serve as kinase inhibitors, playing a crucial role in the development of cancer treatment strategies.
2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96 is used as a chemical building block for the development of novel cancer therapeutics, specifically targeting kinases involved in cancer cell proliferation and survival. Its application in this context is due to its ability to be transformed into potent inhibitors that can effectively combat cancer progression.
Check Digit Verification of cas no
The CAS Registry Mumber 41530-32-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,5,3 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 41530-32:
(7*4)+(6*1)+(5*5)+(4*3)+(3*0)+(2*3)+(1*2)=79
79 % 10 = 9
So 41530-32-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H12O5/c1-12-6-4-5-7(8(10)13-2)9(11)14-3/h4-6H,1-3H3/b6-4+
41530-32-9Relevant articles and documents
PYRIDONE-PYRIMIDINE DERIVATIVE ACTING AS KRASG12C MUTEIN INHIBITOR
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Paragraph 0181-0182, (2020/12/07)
Provided are a class of KRAS G12C mutein inhibitors, which relate in particular to a compound represented by formula (I), an isomer thereof, and a pharmaceutically acceptable salt thereof.
